HDAC3/8 ligand-1
HDAC3/8 ligand-1 (compound 40) is a ligand for target protein for PROTAC that can be used in the synthesis of YX968 (HY-164233).
For research use only. We do not sell to patients.
- Formula: C14H22N4O
- Molecular Weight:262.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
|
HDAC3 |
hHDAC8 |
Chemical Information
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Molecular Weight 262.35
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Formula C14H22N4O
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SMILES
CCCNNC(C(C=C1)=CC=C1N2CCNCC2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (381.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8117 mL | 19.0585 mL | 38.1170 mL | 95.2925 mL |
| 5 mM | 0.7623 mL | 3.8117 mL | 7.6234 mL | 19.0585 mL | |
| 10 mM | 0.3812 mL | 1.9059 mL | 3.8117 mL | 9.5293 mL | |
| 15 mM | 0.2541 mL | 1.2706 mL | 2.5411 mL | 6.3528 mL | |
| 20 mM | 0.1906 mL | 0.9529 mL | 1.9059 mL | 4.7646 mL | |
| 25 mM | 0.1525 mL | 0.7623 mL | 1.5247 mL | 3.8117 mL | |
| 30 mM | 0.1271 mL | 0.6353 mL | 1.2706 mL | 3.1764 mL | |
| 40 mM | 0.0953 mL | 0.4765 mL | 0.9529 mL | 2.3823 mL | |
| 50 mM | 0.0762 mL | 0.3812 mL | 0.7623 mL | 1.9059 mL | |
| 60 mM | 0.0635 mL | 0.3176 mL | 0.6353 mL | 1.5882 mL | |
| 80 mM | 0.0476 mL | 0.2382 mL | 0.4765 mL | 1.1912 mL | |
| 100 mM | 0.0381 mL | 0.1906 mL | 0.3812 mL | 0.9529 mL |