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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
332 Results for "
HIV reverse transcriptase
" in MedChemExpress (MCE) Product Catalog:
Products (332)
332 Results for "HIV reverse transcriptase" in MCE Product Catalog:
20
Target:
Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS .
18
18 Cited Publications
Synonyms: DMP 266; EFV; L-743726
Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture .
17
17 Cited Publications
Synonyms: 2',3'-Dideoxycytidine; ddC; Dideoxycytidine
Target:
Forschungsgebiete:
Zalcitabine is a potent nucleoside analogue reverse transcriptase inhibitor used in the treatment of HIV infection.
14
Target:
Tenofovir alafenamide (GS-7340) is an investigational oral proagent of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor.
14
Target:
Forschungsgebiete:
Doravirine (MK-1439) is a highly specific HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50s of 4.5 nM, 5.5 nM and 6.1 nM against the wild type and K103N and Y181C reverse transcriptase mutants, respectively .
13
13 Cited Publications
Synonyms: Tenofovir DF; Bis(POC)-PMPA fumarate; GS 4331 fumarate
Target:
Forschungsgebiete:
Tenofovir Disoproxil fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B.
13
13 Cited Publications
Synonyms: GS-7340 fumarate
Target:
Tenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral proagent of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor.
13
13 Cited Publications
Synonyms: GS-7340 hemifumarate
Target:
Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an investigational oral proagent of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor.
13
13 Cited Publications
Synonyms: Bis(POC)-PMPA; GS 4331
Target:
Forschungsgebiete:
Tenofovir Disoproxil (Bis(POC)-PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
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11
11 Cited Publications
Synonyms: R278474; TMC278; DB08864
Target:
Forschungsgebiete:
Rilpivirine (R278474) is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM). Rilpivirine has a high genetic barrier to resistance development of HIV .
11
11 Cited Publications
Synonyms: TMC-278 hydrochloride
Rilpivirine (R278474) hydrochloride is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine hydrochloride has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM). Rilpivirine hydrochloride has a high genetic barrier to resistance development of HIV .
10
10 Cited Publications
Synonyms: GS 1278; PMPA
Target:
Forschungsgebiete:
Tenofovir (GS 1278; PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV) .
10
10 Cited Publications
Synonyms: GS 1278 hydrate; PMPA hydrate
Target:
Tenofovir hydrate (GS 1278 hydrate; PMPA hydrate) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV) .
9
9 Cited Publications
Art. -Nr.: HY-17423
CAS. Nr.: 136470-78-5
Target:
Abacavir is an orally active and competitive nucleoside reverse transcriptase inhibitor. Abacavir can inhibits the replication of HIV. Abacavir shows anticancer activity in prostate cancer cell lines. Abacavir can trespass the blood-brain-barrier and suppresses telomerase activity .
9
9 Cited Publications
Art. -Nr.: HY-17423B
CAS. Nr.: 216699-07-9
Target:
Abacavir monosulfate is a competitive, orally active nucleoside reverse transcriptase inhibitor. Abacavir monosulfate can inhibits the replication of HIV. Abacavir monosulfate shows anticancer activity in prostate cancer cell lines. Abacavir monosulfate can trespass the blood-brain-barrier and suppresses telomerase activity .
9
9 Cited Publications
Art. -Nr.: HY-17423A
CAS. Nr.: 188062-50-2
Synonyms: Abacavir Hemisulfate; ABC sulfate
Target:
Abacavir sulfate (Abacavir Hemisulfate) is a competitive, orally active nucleoside reverse transcriptase inhibitor. Abacavir sulfate can inhibits the replication of HIV. Abacavir sulfate shows anticancer activity in prostate cancer cell lines. Abacavir sulfate can trespass the blood-brain-barrier and suppresses telomerase activity .
8
8 Cited Publications
Synonyms: BI-RG 587; NSC 641530; NVP
Target:
Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM .
8
Target:
Forschungsgebiete:
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 value of 0.01 μM in PBMC cells. Emtricitabine inhibits HIV reverse transcriptase, preventing RNA from being transcribed into DNA. Emtricitabine has low brain permeability (logP <0)[1][2][3][4][5].
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Category:
Infection Quinones Anthraquinones Leguminosae Extract Plants Disease Research Fields Senna alexandrina Milll
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
