5 Results for "

High density lipoprotein (human)

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "High density lipoprotein (human)" in MCE Product Catalog:

Cat. No.: HY-NP203
Synonyms: HDL (human)
High density lipoprotein (human) (HDL (human)) is a human-derived high-density lipoprotein. High density lipoprotein can cross the blood-brain barrier, and partially acts on endothelial nitric oxide synthase (eNOS) by activating surface receptors such as SR-B1 and S1P3R, as well as intracellular signaling cascades involving Akt, PI3K and MAPK, thereby inducing the production of NO in endothelial cells. High density lipoprotein (human) can be used in research related to type 2 diabetes, Alzheimer's disease, cancer and atherosclerosis .
loading...
    loading...
Cat. No.: HY-126359
CAS No.: 27098-24-4
Purity:  ≥98.0%
Synonyms: SLPC; 18:0-18:2 PC
1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine (SLPC; 18:0-18:2 PC) is an endogenous phospholipid marker molecule in the glycerophospholipid metabolic pathway. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine is a core component of the phospholipid bilayer of biological membranes and a key responsive lipid for radiation injury and cardiometabolic diseases. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine constitutes the phospholipid bilayers of cell membranes and high-density lipoprotein (HDL), and regulates the core activity of lipoprotein functional homeostasis. The content of 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine in mouse serum shows a significant dose-dependent decrease with increasing ionizing radiation dose, and its level in human HDL also decreases significantly in metabolic syndrome. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine can serve as a biological dosimeter marker for ionizing radiation injury, and is used for rapid and accurate assessment of radiation absorbed dose in exposed individuals. 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine can also act as a lipidomics research target for cardiometabolic diseases such as lipid metabolic syndrome and early-onset coronary heart disease .
loading...
    loading...
Cat. No.: HY-165061
CAS No.: 7019-85-4
Synonyms: Sciadonic acid
Target:  

Apolipoprotein

Research Areas:  

Inflammation/Immunology

5(Z),11(Z),14(Z)-Eicosatrienoic acid (Sciadonic acid), a polyunsaturated fatty acid sourced from maritime pine seed oil, gymnospermae leaves and seeds, and freshwater gastropods, has been shown to reduce high-density lipoprotein and ApoA1 levels in transgenic mice expressing human ApoA1 when included in their diet. In vitro studies indicate that it diminishes cholesterol efflux, and when applied topically in its methyl ester form, it alleviates inflammatory processes, likely by displacing arachidonic acid from phospholipid pools and lowering concentrations of downstream inflammatory mediators such as prostaglandin E2 and leukotrienes.
loading...
    loading...
Cat. No.: HY-NP203A
Synonyms: Dil HDL
Dil high density lipoprotein, human (Dil HDL) is a Dil-labeled human high-density lipoprotein (LDL). High-density lipoprotein (HDL) binds to specific receptors on the surface of vertebrate cells and transports cholesterol via receptor-mediated endocytosis. Dil high density lipoprotein, human can be used to study normal cholesterol transport and endocytosis processes (Ex/Em = 554/571 nm).
loading...
    loading...
Cat. No.: HY-P70873
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPIHBP1; Endothelial Cell LPL Transporter; Glycosylphosphatidylinositol Anchored High density lipoprotein Binding Protein 1; LOC338328; GPI-HBP1; High density lipoprotein-Binding Protein 1; Glycosylphosphatidylinositol-Anchored High density lipoprotein-Bi
Species:  
Human
Source:  
HEK293
loading...
    loading...