1 Result for "

IDH2R140Q-IN-2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "IDH2R140Q-IN-2" in MCE Product Catalog:

Cat. No.: HY-156158
CAS No.: 2749568-16-7
Research Areas:  

Cancer

IDH2 R140Q-IN-2 (compound 36) is an an orally active IDH2 R140Q inhibitor (IC50: 29 nM). IDH2 R140Q-IN-2 reduces D2HG production in TF-1 cell lines expressing mutant IDH2 R140Q (IC50: 10 nM). IDH2 R140Q-IN-2 suppresses D2HG levels in tumor tissue. IDH2 R140Q-IN-2 can be used for research of acute myeloid leukemia (AML) .
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