46 Results for "

IL11

" in MedChemExpress (MCE) Product Catalog:
Products (46)

46 Results for "IL11" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P991218
Synonyms: EnX203
Anti-IL11 Antibody (X203) (EnX203) is a human-derived IgG1, κ type antibody inhibitor, targeting to human IL-11 . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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1
1 Cited Publications
Cat. No.: HY-P7031A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuIL-11; Adipogenesis inhibitory factor; AGIF
Species:  
Source:  
CHO
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1
1 Cited Publications
Cat. No.: HY-P7767
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuCCL27; C-C Motif Chemokine 27; CC Chemokine ILC; Cutaneous T-Cell-Attracting Chemokine; CTACK; Eskine; IL-11 R-Alpha-Locus Chemokine; Skinkine; Small-Inducible Cytokine A27; CCL27; ILC; SCYA27
Species:  
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Cat. No.: HY-P991488

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

BI-765423 is a selective monoclonal antibody inhibitor targeting IL-11. BI-765423 blocks IL-11-mediated signaling, inhibits fibroblast activation, and can extend the healthy lifespan of mammals, counteract cellular senescence in human cells, and alleviate inflammatory aging-related pathological processes. BI-765423 is primarily used in research on fibrotic diseases such as idiopathic pulmonary fibrosis (IPF) .
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Cat. No.: HY-P991487

Research Areas:  

Inflammation/Immunology

LASN01 is a humanized antibody targeting IL-11R, with a Kd of 37 pM. LASN01 blocks the IL-11 signaling pathway via IL-11Rα, and inhibits the phosphorylation of STAT3 and ERK, as well as the expression of pro-inflammatory cytokines, hyaluronic acid, procollagen and fibrotic markers. LASN01 can be used in studies related to thyroid eye disease .
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Cat. No.: HY-P991736
Anti-IL11 Antibody (X203, Mouse IgG) is an antibody targeting IL-11. Anti-IL11 Antibody (X203, Mouse IgG) inhibits IL-11-mediated activation of the ERK-mTORC1 axis, inactivation of LKB1-AMPK, and pro-senescence pathways. Anti-IL11 Antibody (X203, Mouse IgG) alleviates age-related metabolic decline, improves muscle function, reduces tissue fibrosis, decreases the expression of senescence markers, and maintains telomere length and mtDNA copy number. Anti-IL11 Antibody (X203, Mouse IgG) restores browning of white adipose tissue, upregulates thermogenic and mitochondrial biogenesis gene programs, reduces lipid droplet size, and decreases immune cell infiltration in visceral white adipose tissue. Anti-IL11 Antibody (X203, Mouse IgG) extends the median lifespan of mice and reduces the incidence of age-related tumors. Anti-IL11 Antibody (X203, Mouse IgG) can be used in the research of age-related metabolic decline, sarcopenia and age-related cancers .
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Cat. No.: HY-P991219
Synonyms: EnX209

Research Areas:  

Inflammation/Immunology

Anti-IL11RA Antibody (X209) (EnX209) is a human-derived IgG4, κ-type antibody inhibitor targeting IL11RA, with a KD of 6 nM. Anti-IL11RA Antibody (X209) blocks the IL11RA signaling pathway, inhibits ERK-dependent activation, and reduces the activation level of ERK1/2. Anti-IL11RA Antibody (X209) exerts a protective effect against fibrosis. Anti-IL11RA Antibody (X209) is applicable to studies related to liver fibrosis, cardiac fibrosis and other related conditions. Recommended isotype control: Human IgG4 kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-N14323
CAS No.: 184877-64-3
Madindoline A is an orally active gp130 antagonist with a KD of 288 μM. Madindoline A inhibits IL-6- and IL-11-induced osteoclastogenesis, suppresses IL-6-stimulated serum amyloid A protein production, inhibits bone resorption and bone loss, and also inhibits IL-6- and IL-11-dependent cell line growth, as well as IL-6-dependent Stat3 tyrosine phosphorylation. Madindoline A is applicable for the research of hormone-dependent postmenopausal osteoporosis .
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Cat. No.: HY-RS23080
Research Areas:  

Others

Il11 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il11 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS06675
Research Areas:  

Others

IL11 Human Pre-designed siRNA Set A contains three designed siRNAs for IL11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174644
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL11 mRNA encodes the human interleukin 11 (IL11) protein, a member of the gp130 family of cytokines. IL11 is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells.
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Cat. No.: HY-RS16646
Research Areas:  

Others

Il11 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il11 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991489

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

ENx-108A is a human IgG4 monoclonal antibody (mAb) targeting IL-11. BI-765423 can be used in fibrotic diseases research. Recommended isotype control: Human IgG4 kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P700189AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuInterleukin-11/IL-11, Fc ; Interleukin-11; IL11; IL-11
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Cat. No.: HY-P70356
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuInterleukin-11/IL-11, Fc ; Interleukin-11; IL11; IL-11
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Cat. No.: HY-P73155
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-11/IL-11, Fc ; Interleukin-11; IL11; IL-11
Species:  
Source:  
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Cat. No.: HY-P70425
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-11; IL-11; Adipogenesis Inhibitory Factor; AGIF; Oprelvekin; IL11
Species:  
Source:  
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Cat. No.: HY-P76415
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-11; IL11; Adipogenesis Inhibitory Factor; AGIF
Species:  
Source:  
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Cat. No.: HY-174643
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL11RA mRNA encodes the human interleukin 11 receptor subunit alpha (IL11RA) protein, a member of the hematopoietic cytokine receptor family. IL11RA is essential for the normal development of craniofacial bones and teeth.
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Cat. No.: HY-P85220
Synonyms: IL11; Interleukin-11; IL-11; Adipogenesis inhibitory factor; AGIF; Oprelvekin

Host:  

Mouse

Application:  

WB, ICC/IF, IP, ELISA, IF-Tissue

Reactivity:  

Human, Mouse, Rat

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