2 Results for "

IRF1-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "IRF1-IN-1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-171006
CAS No.: 701225-07-2
IRF1-IN-1 (Compound I-2) is an IRF1 inhibitor. IRF1-IN-1 decreases the recruitment of IRF1 to the promoter of CASP1. IRF1-IN-1 inhibits cell death signaling pathway (i.e., cleavage of Caspase 1, GSDMD, IL-1 and PARP1). IRF1-IN-1 has a protective effect on ionizing radiation-induced inflammatory skin injury .
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Cat. No.: HY-176222
Target:  

Caspase

Research Areas:  

Inflammation/Immunology

IRF1 antagonist 1 (8003-3282) is a potent IRF1 (interferon regulatory factor) antagonist with anti-inflammatory activity. IRF1 antagonist 1 can maintain blood-brain barrier integrity and reduce brain edema. IRF1 antagonist 1 can improve neurological outcomes in an acute traumatic brain injury (TBI) mouse model .
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