4 Results for "

KBM-5 cells

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "KBM-5 cells" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P1832A
Target:  

NF-κB Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

PTD-p65-P1 Peptide TFA is a potent, selective nuclear transcription factor NF-κB inhibitor and derives from the p65 subunit of NF-κB amino acid residues 271-282, which selectively inhibits NF-κB activation induced by various inflammatory stimulation, down-regulate NF-κB-mediated gene expression and up-regulate apoptosis .
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Cat. No.: HY-14942A
CAS No.: 293736-67-1
Purity:  95.08%
Synonyms: RTA 744; WP 744; WP 769 hydrochloride
Berubicin (RTA 744) hydrochloride is a Doxorubicin (HY-15142A) analog that can cross the blood-brain barrier. Berubicin hydrochloride inhibits P-gp and MRP1-mediated efflux and suppresses glioblastoma multiforme (GBM). Berubicin hydrochloride exerts toxic effects on leukemia cells by activating nuclear factor κB (NF-κB) and induces apoptosis in neuroblastoma cells. Berubicin hydrochloride can be used in the study of tumors related to the nervous system .
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Cat. No.: HY-P1832
Target:  

NF-κB Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

PTD-p65-P1 Peptide is a potent, selective nuclear transcription factor NF-κB inhibitor and derives from the p65 subunit of NF-κB amino acid residues 271-282, which selectively inhibits NF-κB activation induced by various inflammatory stimulation, down-regulate NF-κB-mediated gene expression and up-regulate apoptosis .
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Cat. No.: HY-100702
CAS No.: 701976-54-7
Target:  

Akt Apoptosis

Research Areas:  

Cancer

SH-5 is a potent AKT inhibitor. SH-5 potentiates the apoptosis induced by tumor necrosis factor. SH-5 blocks NF-kB activation induced by TNF-a, lipopolysaccharide (HY-D1056), phorbol ester (HY-18739), and cigarette smoke .
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