Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
KCNT1-IN-1
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "KCNT1-IN-1" in MCE Product Catalog:
Cat. No.: HY-175335
CAS No.: 3087554-10-4
Synonyms: KCNT1-IN-1
Target:
Research Areas:
WO662 (compound I-1a) is a KCNT1 inhibitor with an IC50 ≤ 250 nM. WO662 can be used in the research of neurological diseases .
Cat. No.: HY-179093
CAS No.: 2540501-85-5
Target:
Research Areas:
KCNT1-IN-3 (Compound 31) is a KCNT1 inhibitor with an IC50 value of 30 nM against the wild-type human KCNT1. KCNT1-IN-3 can be used in the research of epilepsy .
Cat. No.: HY-159958
CAS No.: 3037315-44-6
Target:
Research Areas:
KNa1.1-IN-2 (Compound Z05) is a selective KNa1.1 channel inhibitor with blood-brain barrier penetration, particularly effective against the hERG channel. KNa1.1-IN-2 works by binding to the KNa1.1 channel and blocking the channel activity induced by Gain-of-function (GOF) mutations, effectively intervening in KCNT1-related epilepsy. Additionally, KNa1.1-IN-2 inhibits the GOF mutant Y796H. KNa1.1-IN-2 holds promise for research into KCNT1-related epilepsy disorders .
Cat. No.: HY-P0058S
Research Areas:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
