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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
KG-FP-003
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "KG-FP-003" in MCE Product Catalog:
Cat. No.: HY-186117
CAS No.: 3066008-42-9
KG-FP-003 is a highly potent, selective, and durable TEAD PROTAC degrader (TEAD1 DC50 = 6 ± 4 nM, TEAD2 DC50 = 68 ± 15 nM, TEAD3 DC50 = 12 ± 5 nM, TEAD4 DC50 = 7 ± 5 nM). KG-FP-003 promotes ubiquitination and degradation of TEAD. KG-FP-003 exhibits anticancer activity against mesothelioma and ovarian cancer .
Cat. No.: HY-186118
Research Areas:
TEAD ligand 6 is a TEAD ligand. TEAD ligand 6 serves as a ligand for target protein for PROTAC (Ligands for Target Protein for PROTAC) and is used to develop and design PROTAC-based TEAD degraders, such as KG-FP-003 (HY-186117). TEAD ligand 6 applies to glioblastoma research .
Cat. No.: HY-186119
Research Areas:
E3 Ligase Ligand-linker Conjugate 228 is an E3 ligase CRBN ligand-linker conjugate composed of 2-(4-(2,4-Dioxotetrahydropyrimidin-1 (2H)-yl)-3-methylphenoxy) acetic acid (HY-W733199) and a linker. E3 ligase ligand-linker conjugates can be used to synthesize degraders of PROTAC TEAD, such as KG-FP-003 (HY-186117). E3 Ligase Ligand-linker Conjugate 228 can be applied to glioblastoma research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
