E3 Ligase Ligand-linker Conjugate 228
E3 Ligase Ligand-linker Conjugate 228 is an E3 ligase CRBN ligand-linker conjugate composed of 2-(4-(2,4-Dioxotetrahydropyrimidin-1 (2H)-yl)-3-methylphenoxy) acetic acid (HY-W733199) and a linker. E3 ligase ligand-linker conjugates can be used to synthesize degraders of PROTAC TEAD, such as KG-FP-003 (HY-186117). E3 Ligase Ligand-linker Conjugate 228 can be applied to glioblastoma research.
For research use only. We do not sell to patients.
- Formula: C31H45N5O5
- Molecular Weight:567.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
Cereblon |
Chemical Information
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Molecular Weight 567.72
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Formula C31H45N5O5
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SMILES
O=C(N(CC1)CCC1CC(CC2)CCN2C(C(CC3)CCC3N)=O)COC4=CC=C(C(C)=C4)N5CCC(NC5=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)