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3 Results for "
KSP ATPase
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "KSP ATPase" in MCE Product Catalog:
PVZB1194 is a biphenyl-type
inhibitor of Kinesin-5 ATPase activity that binds to the α4/α6 site of the motor domain in a nucleotide competitive manner. PVZB1194 has an IC50 of 0.12 μM for KSP ATPase. PVZB1194 induces mitotic arrest with the formation of a monopolar spindle, and inhibits HeLa cells proliferatio (IC50: 5.5 μM). PVZB1194 can be used in the study of tumors .
Cat. No.: HY-122130
CAS No.: 1146209-50-8
Synonyms: MK-8267
SCH 2047069 (MK-8267) is an orally active kinesin spindle protein (KSP) inhibitor (Kd: 0.5 nM) that can cross the blood-brain barrier. SCH 2047069 exhibits an IC50 value of ≤ 5 nM against the KSP ATPase. SCH 2047069 exhibits broad-spectrum antitumor activity. SCH 2047069 can induce mitotic arrest and apoptosis in tumor cells. SCH 2047069 can be used in the research of tumors such as ovarian cancer, colon cancer, glioblastoma, and lymphoma .
Cat. No.: HY-W198426
CAS No.: 13262-48-1
Synonyms: Biphenyl-4-ylurea; (4-Phenylphenyl)urea
Target:
Research Areas:
1-(-4-yl) urea (compound 44) is a biphenyl urea analog .
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Protocols
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