1 Result for "

LEOPARD syndrome

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LEOPARD syndrome" in MCE Product Catalog:

Cat. No.: HY-175803
CAS No.: 2818955-47-2
Target:  

SHP2 ERK

Research Areas:  

Cancer

SHP2-IN-44 (Compound 26) is an allosteric and orally active SHP2 inhibitor with an IC50 of 27 ?nM. SHP2-IN-44 also inhibits ERK phosphorylation (IC50 of 299 ?nM) without off-target hERG activity. SHP2-IN-44 has a broad-spectrum anticancer activity, such as juvenile myelomonocytic leukemia, neuroblastoma and breast cancer. SHP2-IN-44 can be used for Noonan syndrome, LEOPARD syndrome and cancers research .
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