27 Results for "

MAPK14

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "MAPK14" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-10401
CAS No.: 745833-23-2
Purity:  99.54%
Target:  

p38 MAPK Autophagy

Research Areas:  

Inflammation/Immunology

VX-702 is a highly selective inhibitor of p38α MAPK, 14-fold higher potency against the p38α versus p38β .
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3
3 Cited Publications
Cat. No.: HY-P80842
Synonyms: MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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2
2 Cited Publications
Cat. No.: HY-18874
CAS No.: 443913-15-3
Target:  

p38 MAPK Autophagy

Research Areas:  

Others

p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay .
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2
2 Cited Publications
Cat. No.: HY-P80776
Synonyms: MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein

Host:  

Mouse

Application:  

WB

Reactivity:  

Human, Mouse, Rat, Monkey

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2
2 Cited Publications
Cat. No.: HY-P80777
Synonyms: MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human

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2
2 Cited Publications
Cat. No.: HY-P80996
Synonyms: CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A, MAPK14, Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, Stress-activated protein kinase 2a, CSAID-binding protein, MAP kinase p38 alpha, SAPK2a

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-N7922
CAS No.: 91485-02-8
Synonyms: Decarboxyellagic acid
Urolithin M5 (Decarboxyellagic acid) is an orally active influenza virus neuraminidase inhibitor and neuroprotective agent, with IC50 values of 174.8 μM (HK68), 191.5 μM (pdm09), 243.2 μM (WSN) and 257.1 μM (PR8) against four influenza virus neuraminidases, respectively. Urolithin M5 inhibits viral neuraminidase activity, thereby blocking influenza virus replication (including oseltamivir (HY-13317)-resistant strains), protecting infected mammals from death and improving pulmonary edema. Urolithin M5 forms a hydrogen-bond stabilized complex with IGF1R, and binds to MAPK14, AKT1, NFKB1 and EGFR. Urolithin M5 reduces reactive oxygen species production, inhibits neuronal apoptosis, restores mitochondrial transmembrane potential, and promotes neurite outgrowth of damaged neuronal cells. Urolithin M5 can be used in research related to influenza virus infection and Alzheimer's disease .
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1
1 Cited Publications
Cat. No.: HY-P80776A
Synonyms: p38 (phospho T180 + Y182); p-p38 (phospho T180 + Y182); p38 (phospho T180/Y182); CSAID Binding Protein 1; CSAID binding protein; CSAID-binding protein; Csaids binding protein; CSBP 1; CSBP 2; CSBP; CSBP1; CSBP2; CSPB 1; CSPB1; Cytokine suppressive anti inflammatory drug binding protein; Cytokine suppressive anti-inflammatory drug-binding protein; EXIP; MAP kinase 14; MAP kinase MXI2; MAP kinase p38 alpha; MAPK 14; MAPK14; MAX interacting protein 2; MAX-interacting protein 2; Mitogen Activated Protein Kinase 14; Mitogen activated protein kinase p38 alpha; Mitogen-activated protein kinase 14; Mitogen-activated protein kinase p38 alpha; MK14_HUMAN; Mxi 2; Mxi2; p38 ALPHA; p38; p38 MAP kinase; p38 MAPK; p38 mitogen activated protein kinase; p38ALPHA; p38alpha Exip; PRKM14; PRKM15; RK; SAPK 2A; SAPK2A; Stress Activated Protein Kinase 2A.

Host:  

Rabbit

Application:  

WB, IHC-P, FC, ICC/IF, ELISA

Reactivity:  

Human, Mouse

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Cat. No.: HY-123961
CAS No.: 2230821-68-6
Purity:  99.33%
Research Areas:  

Cancer

SJF-8240 is a selective p38α and c-Met PROTAC degrader. SJF-8240 promotes the ubiquitination and selective degradation of p38α and c-Met. SJF-8240 is applicable to breast cancer-related research .
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Cat. No.: HY-148061
CAS No.: 2769753-53-7
Purity:  99.28%
DB1113 (Example 24) is a bifunctional compound targeted protein degradation of kinases. DB1113 degrades ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2, and ULK1. DB1113 can be used for research of disease or disorder mediated by aberrant kinase activity .
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Cat. No.: HY-RS08107
Research Areas:  

Others

MAPK14 Human Pre-designed siRNA Set A contains three designed siRNAs for MAPK14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-148063
CAS No.: 2769753-47-9
Purity:  98.80%
DB0614 is a PROTAC based on Cereblon ligand, which is a selective and potent targeted protein degrader of NEK9 inhibitor. DB0614 can degrade ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2 and ULK1. DB0614 can be used for research of disease or disorder mediated by aberrant kinase activity .(Blue: Thalidomide-4-OH (HY-103596), Black: linker, Pink: FLT3-IN-17 (HY-148070))
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Cat. No.: HY-RS08108
Research Areas:  

Others

Mapk14 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mapk14 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS08109
Research Areas:  

Others

Mapk14 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mapk14 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-10401R
CAS No.: 745833-23-2
VX-702 (Standard) is the analytical standard of VX-702. This product is intended for research and analytical applications. VX-702 is a highly selective inhibitor of p38α MAPK, 14-fold higher potency against the p38α versus p38β .
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Cat. No.: HY-W015329
CAS No.: 702-82-9
Research Areas:  

Others

3-Amino-1-adamantanol is a p38α‑TAB1 interaction inhibitor. 3-Amino-1-adamantanol occupies the non-canonical docking site of p38α, inhibits the phosphorylation of TAB1 by activated pp38α, and disrupts the formation of the p38α‑TAB1 protein complex. 3-Amino-1-adamanol is applicable to research related to myocardial ischemic injury; it also serves as an intermediate for the synthesis of compounds such as Vildagliptin (HY-14291) .
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Cat. No.: HY-186241
CAS No.: 2392969-05-8
Target:  

p38 MAPK

Research Areas:  

Inflammation/Immunology

NuP-3 is an orally active dual inhibitor of MAPK13 (IC50 < 250 nM), MAPK14 (IC50 = 7 nM), MAPK12 and MAPK11. NuP-3 blocks airway inflammation and mucus production. NuP-3 is used for the research of respiratory system diseases .
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Cat. No.: HY-N21965
CAS No.: 488-02-8
Thesinine is a saturated pyrrolizidine alkaloid isolated from the seeds and flowers of *Borago officinalis*; it is the primary alkaloid in borage seeds and the only alkaloid present in borage flowers. In silico predictions indicate that Thesinine binds to the AKT1, MAPK3, MMP9, and MAPK14 proteins. Thesinine is applicable to research related to skin aging
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Cat. No.: HY-N18209
CAS No.: 74459-23-7
4-Hydroxy-3-butylphthalide is a Phthalide (HY-W015820) derivative found in the rhizome of Ligusticum ChuanXiong Hort. 4-Hydroxy-3-butylphthalide binds core targets linked to lung cancer brain metastasis, such as BDNF, FOS, and MAPK14. 4-Hydroxy-3-butylphthalide can be used for the research of lung cancer brain metastasis .
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Cat. No.: HY-P73335
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MAPK14; SAPK2A; Prev. CSBP1; Cytokine Suppressive Anti-Inflammatory Drug Binding Protein; Prev. CSBP2; Cytokine Suppressive Anti-Inflammatory Drug-Binding Protein; Prev. CSPB1; P38 Mitogen Activated Protein Kinase; Mitogen-Activated Protein Kinase P38 Alp
Species:  
Source:  
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