702-82-9
Chemical Structure
3-Amino-1-adamantanol
- No. CAS: 702-82-9
- Formula:C10H17NO
- Molecular Weight:167.25
IUPAC Name: (1s,3r,5R,7S)-3-aminoadamantan-1-ol
InChIKey: DWPIPTNBOVJYAD-FIRGSJFUSA-N
SMILES: O[C@]1(C2)C[C@@H]3C[C@@H](C[C@@]2(N)C3)C1
Biological Activity: 3-Amino-1-adamantanol is a p38α‑TAB1 interaction inhibitor. 3-Amino-1-adamantanol occupies the non-canonical docking site of p38α, inhibits the phosphorylation of TAB1 by activated pp38α, and disrupts the formation of the p38α‑TAB1 protein complex. 3-Amino-1-adamanol is applicable to research related to myocardial ischemic injury; it also serves as an intermediate for the synthesis of compounds such as Vildagliptin (HY-14291)[1].
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3-Amino-1-adamantanol | 99.67% | 3-Amino-1-adamantanol is a p38α‑TAB1 interaction inhibitor. 3-Amino-1-adamantanol occupies the non-canonical docking site of p38α, inhibits the phosphorylation of TAB1 by activated pp38α, and disrupts the formation of the p38α‑TAB1 protein complex. 3-Amino-1-adamanol is applicable to research related to myocardial ischemic injury; it also serves as an intermediate for the synthesis of compounds such as Vildagliptin (HY-14291). | ||||||||||||||||||||
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