2392969-05-8
Chemical Structure
NuP-3
- CAS. Nr.: 2392969-05-8
- Formula:C24H24ClFN4O3
- Molecular Weight:470.92
InChIKey: RULQJYJGZIDWAX-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C(C)(C)C)=CC=C1Cl)NC2=CC=C(C=C2F)OC3=CC(NC(C)=O)=NC=C3
Biological Activity: NuP-3 is an orally active dual inhibitor of MAPK13 (IC50 < 250 nM), MAPK14 (IC50 = 7 nM), MAPK12 and MAPK11. NuP-3 blocks airway inflammation and mucus production. NuP-3 is used for the research of respiratory system diseases[1].
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NuP-3 | NuP-3 is an orally active dual inhibitor of MAPK13 (IC50 < 250 nM), MAPK14 (IC50 = 7 nM), MAPK12 and MAPK11. NuP-3 blocks airway inflammation and mucus production. NuP-3 is used for the research of respiratory system diseases. | |||||||||||||||||||||
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Keywords