488-02-8
488-02-8
Chemical Structure
Thesinine
- CAS No.: 488-02-8
- Formula:C17H21NO3
- Molecular Weight:287.35
InChIKey: FQVNMXZPGWLUFZ-BNVCYRGBSA-N
SMILES: OC(C=C1)=CC=C1/C=C/C(OC[C@H]2[C@]3([H])N(CCC3)CC2)=O
Biological Activity: Thesinine is a saturated pyrrolizidine alkaloid and the primary alkaloid found in the seeds and flowers of Borago officinalis. Thesinine binds to AKT1, MAPK3, MMP9, and MAPK14 proteins as predicted by in silico analysis. Thesinine is applicable to research related to skin aging[1][2]
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Thesinine | Thesinine is a saturated pyrrolizidine alkaloid and the primary alkaloid found in the seeds and flowers of Borago officinalis. Thesinine binds to AKT1, MAPK3, MMP9, and MAPK14 proteins as predicted by in silico analysis. Thesinine is applicable to research related to skin aging | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Cho MH, et al. An Integrated Systems Pharmacology Approach Combining Bioinformatics, Untargeted Metabolomics and Molecular Dynamics to Unveil the Anti-Aging Mechanisms of Tephroseris flammea. Biomolecules. 2025 Dec 15;15(12):1740. [Content Brief]
- [2]. Dodson C D, et al. Pyrrolizidine alkaloids from borage (Borago officinalis) seeds and flowers[J]. Journal of Natural products, 1986, 49(4): 727-728.
Keywords
