2 Results for "

MEK-IN-5

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "MEK-IN-5" in MCE Product Catalog:

Cat. No.: HY-143468
CAS No.: 2417022-06-9
Target:  

Apoptosis MEK

Research Areas:  

Cancer

MEK-IN-5 is a potent MEK inhibitor and NO donor. MEK-IN-5 significantly reduces the levels of pMEK and pERK in a dose-dependent and time-dependent manner. MEK-IN-5 induces apoptosis in MDA-MB-231 cells .
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3
3 Cited Publications
Cat. No.: HY-15196
CAS No.: 871026-44-7
Purity:  99.70%
Target:  

EGFR

Research Areas:  

Cancer

TAK-285 is a potent, selective, ATP-competitive and orally active HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, respectively. TAK-285 is >10-fold selectivity for HER1/2 than HER4, and less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. TAK-285 has effective antitumor activity . TAK-285 can cross the blood-brain barrier (BBB) .
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