2417022-06-9
2417022-06-9
Chemical Structure
MEK-IN-5
- CAS No.: 2417022-06-9
- Formula:C29H27FN4O10S2
- Molecular Weight:674.67
InChIKey: CDBIMQWJMSNOMN-UHFFFAOYSA-N
SMILES: O=C1OC2=C(C(C)=C1CC3=C(F)C(NS(=O)(NC)=O)=CC=C3)C=CC(OCCCOC4=NO[N+]([O-])=C4S(=O)(C5=CC=CC=C5)=O)=C2
Biological Activity: MEK-IN-5 is a potent MEK inhibitor and NO donor. MEK-IN-5 significantly reduces the levels of pMEK and pERK in a dose-dependent and time-dependent manner. MEK-IN-5 induces apoptosis in MDA-MB-231 cells[1].
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MEK-IN-5 | MEK-IN-5 is a potent MEK inhibitor and NO donor. MEK-IN-5 significantly reduces the levels of pMEK and pERK in a dose-dependent and time-dependent manner. MEK-IN-5 induces apoptosis in MDA-MB-231 cells. | |||||||||||||||||||||
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