2 Results for "

Mersalyl

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Mersalyl" in MCE Product Catalog:

Cat. No.: HY-108868
CAS No.: 492-18-2
Purity:  ≥80.0%
Synonyms: Salirgan; Salurin; Salyrgan
Research Areas:  

Metabolic Disease

Mersalyl (Salirgan) is a potent vascular endothelial growth factor (VEGF) and hypoxia-inducible factor 1 (HIF-1) inducer. Mersalyl induces VEGF and ENO1 mRNA expression. Mersalyl shows diuresis effects .
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Cat. No.: HY-124470
CAS No.: 550-28-7
Target:  

Others

Research Areas:  

Cardiovascular Disease

Amisometradine is an orally active aminouracil diuretic with a diuretic potency approximately 40% that of Mersalyl (HY-108868) (when administered intramuscularly). Amisometradine exerts its effects by promoting the excretion of sodium, chloride and a small amount of potassium, exhibits significant therapeutic effects in heart failure models, and has good tolerance with long-term administration. Compared with drugs of the same class, Amisometradine causes fewer gastrointestinal reactions; its minor side effects mainly include nausea, vomiting, diarrhea, tinnitus and deafness, and are usually not accompanied by proteinuria or abnormalities in blood and urine indicators. Amisometradine is an important tool for the study of heart failure and related diuretic mechanisms .
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