492-18-2
492-18-2
Chemical Structure
Mersalyl
Synonym(s): Salirgan; Salurin; Salyrgan
- CAS No.: 492-18-2
- Formula:C13H16HgNNaO6
- Molecular Weight:505.85
InChIKey: OSKJPYUSIVPQGP-UHFFFAOYSA-L
SMILES: [O-]C(COC1=C(C(NCC2OC)=[O][Hg+2]([CH2-]2)[OH-])C=CC=C1)=O.[Na+]
Biological Activity: Mersalyl (Salirgan) is a potent vascular endothelial growth factor (VEGF) and hypoxia-inducible factor 1 (HIF-1) inducer. Mersalyl induces VEGF and ENO1 mRNA expression. Mersalyl shows diuresis effects[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mersalyl | 89.25% | Mersalyl (Salirgan) is a potent vascular endothelial growth factor (VEGF) and hypoxia-inducible factor 1 (HIF-1) inducer. Mersalyl induces VEGF and ENO1 mRNA expression. Mersalyl shows diuresis effects. | ||||||||||||||||||||
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References
- [1]. Kowaltowski AJ, et al. Mitochondrial membrane protein thiol reactivity with N-ethylmaleimide or mersalyl is modified by Ca2+: correlation with mitochondrial permeability transition. Biochim Biophys Acta. 1997 Feb 15;1318(3):395-402. [Content Brief]
- [2]. Agani F, et al. Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor 1 activity. Mol Pharmacol. 1998 Nov;54(5):749-54. [Content Brief]
- [3]. FARAH A, et al. Histochemical studies on the site of action of mercurial diuretics. J Histochem Cytochem. 1955 Jul;3(4):271-3. [Content Brief]
Keywords
