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Cat. No.: HY-105742

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Alloclamide

Alloclamide is a competitive antihistamine compound targeting the H₁ histamine receptor. Alloclamide‘s core regulatory mechanism involves competitive binding to the H₁ histamine receptor, blocking the activation of the receptor by histamine molecules and inhibiting various allergy-related biological responses mediated by histamine. Alloclamide can be used in allergy-related research.

For research use only. We do not sell to patients.

CAS No.: 5486-77-1
Formula: C₁₆H₂₃ClN₂O₂
Molecular Weight:310.82

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Alloclamide Chemical Structure

CAS No.: 5486-77-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

H₁ Receptor

All Histamine Receptor Isoforms :

In Vitro

Alloclamide (prepared as a 400 mg/L stock solution in methanol; diluted with 0.04 M Brij35 pH 7.4 buffer) yields retention parameters log k of 1.89 (0.02 M Brij35), 1.55 (0.04 M Brij35), and 1.45 (0.06 M Brij35) under chromatographic detection conditions of 36.5 ℃ and 240 nm^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 5486-77-1
Molecular Weight 310.82
Formula C₁₆H₂₃ClN₂O₂
SMILES

O=C(NCCN(CC)CC)C1=CC=C(Cl)C=C1OCC=C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Quiñones-Torrelo C, et al. Retention pharmacokinetic and pharmacodynamic parameter relationships of antihistamine drugs using biopartitioning micellar chromatography. Journal of chromatography. B, Biomedical sciences and applications. 2001 Sep 15;761(1):13-26. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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Alloclamide

All Histamine Receptor Isoforms