19 Results for "

Mevalonic Acid

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "Mevalonic Acid" in MCE Product Catalog:

12
12 Publications Verification
製品番号: HY-113071A
CAS 番号: 2618458-93-6
純度:  ≥98.0%
別名: MVA lithium salt
Mevalonic acid (MVA) lithium salt is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid lithium salt is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid lithium salt can be used in studies of myopathy and heart failure .
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1 Cited Publications
製品番号: HY-107855
CAS 番号: 674-26-0
純度:  99.15%
別名: (±)-Mevalonolactone; Mevalolactone
DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy . DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling [2][4].
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製品番号: HY-N9474
CAS 番号: 108869-00-7
別名: 5-DiphosphoMevalonic Acid tetralithium; Mevalonic Acid 5-diphosphate tetralithium
Mevalonic acid 5-pyrophosphate (5-Diphosphomevalonic acid) tetralithium is an endogenous metabolite of the mevalonate pathway .
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製品番号: HY-113071
CAS 番号: 150-97-0
別名: MVA
Mevalonic acid (MVA) is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure .
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製品番号: HY-143996S
CAS 番号: 2747918-57-4
純度:  ≥99.0%
Mevalonic acid- 13C,d3 (sodium) is the 13C- and deuterium labeled Mevalonic acid .
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製品番号: HY-135700
CAS 番号: 19115-49-2
純度:  ≥98.0%
Mevalonolactone is an intermediate metabolite in the eukaryotic mevalonate pathway, serving as the stable δ-lactone form of mevalonate with oral activity. Mevalonolactone exhibits binding affinity for ZNF384 (Ka = 12.6 μM) and inhibitory activity against aconitase (aconitase). Mevalonolactone promotes the nuclear localization of ZNF384 and enhances its binding to the GGPPS promoter. Mevalonolactone induces insulin resistance, disrupts glucose and lipid metabolism, enhances the isoprenylation of K-Ras, and inhibits the activation of the insulin signaling pathway. Mevalonolactone inhibits polypeptide synthesis of HMG-CoA reductase in isolated rat hepatocytes, promotes its degradation, and reduces its enzymatic activity. Mevalonolactone impairs mitochondrial function in rat brains. Mevalonolactone promotes the development of metabolically unhealthy obesity. Mevalonolactone can be used in research related to metabolically abnormal obesity, mevalonic aciduria, HMGCR-related limb-girdle myopathy, and statin-induced myopathy .
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製品番号: HY-107855S
CAS 番号: 347840-19-1
純度:  99.27%
別名: (±)-Mevalonolactone-d7; Mevalolactone-d7
DL-Mevalonolactone-d7 is the deuterium labeled DL-Mevalonolactone. DL-Mevalonolactone ((±)-Mevalonolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (?Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling .
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製品番号: HY-113071C
CAS 番号: 32451-23-3
別名: (S)-MVA
(S)-Mevalonic acid is the isomer of Mevalonic acid (HY-113071). Mevalonic acid ((S)-DCIT) is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure .
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製品番号: HY-113071AR
CAS 番号: 2618458-93-6
別名: MVA lithium salt (Standard)
Mevalonic acid lithium salt (Standard) is the analytical standard of Mevalonic acid lithium salt. This product is intended for research and analytical applications. Mevalonic acid (MVA) lithium salt is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid lithium salt is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid lithium salt can be used in studies of myopathy and heart failure .
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製品番号: HY-W700346
CAS 番号: 1215802-31-5
D,L-Mevalonic acid (dicyclohexylammonium) is a kind of biochemical reagent.
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製品番号: HY-126746
CAS 番号: 4423-58-9
Category:  

天然物 Microorganisms

Target:  

Antibiotic

Corynecin I is an antibiotic produced by Corynebacterium hydrocarboclastus, and its precursor (D-(-) threo-p-amino phenyl serinol-N-acetylamine) has a minimal inhibitory effect on the synthesis of Corynecin from mevalonic acid .
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製品番号: HY-107855S1
CAS 番号: 61219-76-9
別名: (±)-Mevalonolactone-d3; Mevalolactone-d3
DL-Mevalonolactone-d3 is the deuterium labeled DL-Mevalonolactone . DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential ( Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling .
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製品番号: HY-W725424
CAS 番号: 96949-03-0
別名: (R)-MVA sodium
Target:  

Drug Isomer

研究分野:  

Others

(R) -Mevalonic acid ( (R) -MVA) sodium is an isomer of Mevalonic acid (HY-113071) . Mevalonic acid (MVA) is a precursor substance in the mevalonate pathway and is crucial for cell growth and proliferation.
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製品番号: HY-107855R
CAS 番号: 674-26-0
別名: (±)-Mevalonolactone (Standard); Mevalolactone (Standard)
DL-Mevalonolactone (Standard) is the analytical standard of DL-Mevalonolactone. This product is intended for research and analytical applications. DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy . DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling .
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製品番号: HY-N10619
CAS 番号: 1164-45-0
Gibberellin A12 is a free C20-gibberellin, serving as a gibberellin biosynthesis intermediate and metabolite precursor. Gibberellin A12 exists in maturing Sechium edule seed testa, developing Pisum sativum seeds and Gibberella fujikuroi .
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製品番号: HY-N19716
CAS 番号: 34427-31-1
Austamide is an indole alkaloid found in cultures of Aspergillus ustus. Austamide undergoes biosynthesis via the classical mevalonate pathway with nonface-selective reverse prenylation of its indole ring .
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製品番号: HY-107855S2
CAS 番号: 53771-22-5
別名: (±)-Mevalonolactone-13C; Mevalolactone-13C
DL-Mevalonolactone- 13C ((±)-Mevalonolactone- 13C) is the 13C-labeled DL-Mevalonolactone (HY-107855). DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy. DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling.
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製品番号: HY-107855S4
CAS 番号: 287111-36-8
別名: (±)-Mevalonolactone-13C2; Mevalolactone-13C2
DL-Mevalonolactone- 13C2 ((±)-Mevalonolactone- 13C2) is the 13C-labeled DL-Mevalonolactone (HY-107855). DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy . DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling [2][4].
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製品番号: HY-W752587
CAS 番号: 349553-98-6
別名: (±)-Mevalonolactone-d4; Mevalolactone-d4
DL-Mevalonolactone-d4 ( (±)-Mevalonolactone-d4) is the deuterium labeled DL-Mevalonolactone (HY-107855). DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy . DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling .
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