32451-23-3
32451-23-3
Chemical Structure
(S)-Mevalonic acid
Synonym(s): (S)-MVA
- CAS No.: 32451-23-3
- Formula:C6H12O4
- Molecular Weight:148.16
IUPAC Name: (S)-3,5-dihydroxy-3-methylpentanoic acid
InChIKey: KJTLQQUUPVSXIM-LURJTMIESA-N
SMILES: O=C(O)C[C@@](C)(O)CCO
Biological Activity: (S)-Mevalonic acid is the isomer of Mevalonic acid (HY-113071). Mevalonic acid ((S)-DCIT) is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure[1][2].
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(S)-Mevalonic acid | (S)-Mevalonic acid is the isomer of Mevalonic acid (HY-113071). Mevalonic acid ((S)-DCIT) is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure. | |||||||||||||||||||||
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References
- [1]. Moschetti A, et al. Coenzyme Q nanodisks counteract the effect of statins on C2C12 myotubes. Nanomedicine. 2021 Oct;37:102439. [Content Brief]
- [2]. Soma MR, et al. Cholesterol and mevalonic acid modulation in cell metabolism and multiplication. Toxicol Lett. 1992 Dec;64-65 Spec No:1-15. [Content Brief]
