Mevalonic acid (Synonyms: MVA)

Cat. No.: HY-113071: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Mevalonic acid (MVA) is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure.

The free form of the compound is prone to instability, it is advisable to consider the stable salt form (Mevalonic acid lithium salt) that retains the same biological activity.

For research use only. We do not sell to patients.

Mevalonic acid Chemical Structure

CAS No. : 150-97-0

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5 mg	Get quote	Estimated Time of Arrival: December 31
10 mg	Get quote	Estimated Time of Arrival: December 31
25 mg	Get quote	Estimated Time of Arrival: December 31

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Other Forms of Mevalonic acid:

Mevalonic acid lithium salt In-stock

8 Publications Citing Use of MCE Mevalonic acid

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Biological Activity
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References
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Description

In Vitro

Mevalonic acid (80, 90, 100, 110 µM; 72 h) shows prevention of simvastatin-induced loss of viability of C2C12myotube cells in vitro^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:	C2C12 cells (simvastatin-induced)
Concentration:	80, 90, 100, 110 µM
Incubation Time:	72 h
Result:	Showed no decline in cell viability.

Clinical Trial

Molecular Weight

148.16

Formula

C₆H₁₂O₄

CAS No.

150-97-0

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CC(C)(O)CCO

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Microorganisms

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Purity: ≥99.0%

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Data Sheet (269 KB) SDS (251 KB)

COA (243 KB)

Handling Instructions (2659 KB)

References

[1]. Moschetti A, et al. Coenzyme Q nanodisks counteract the effect of statins on C2C12 myotubes. Nanomedicine. 2021 Oct;37:102439. [Content Brief]

[2]. Soma MR, et al. Cholesterol and mevalonic acid modulation in cell metabolism and multiplication. Toxicol Lett. 1992 Dec;64-65 Spec No:1-15. [Content Brief]

Mevalonic acid Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mevalonic acid150-97-0MVAEndogenous Metabolitemevalonate pathwaymyopathyheart failureC2C12Inhibitorinhibitorinhibit

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