150-97-0
150-97-0
Chemical Structure
Mevalonic acid
Synonym(s): MVA
- CAS. Nr.: 150-97-0
- Formula:C6H12O4
- Molecular Weight:148.16
IUPAC Name: 3,5-dihydroxy-3-methylpentanoic acid
InChIKey: KJTLQQUUPVSXIM-UHFFFAOYSA-N
SMILES: O=C(O)CC(C)(O)CCO
Biological Activity: Mevalonic acid (MVA) is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure[1][2].
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Mevalonic acid | Mevalonic acid (MVA) is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure. | |||||||||||||||||||||
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References
- [1]. Moschetti A, et al. Coenzyme Q nanodisks counteract the effect of statins on C2C12 myotubes. Nanomedicine. 2021 Oct;37:102439. [Content Brief]
- [2]. Soma MR, et al. Cholesterol and mevalonic acid modulation in cell metabolism and multiplication. Toxicol Lett. 1992 Dec;64-65 Spec No:1-15. [Content Brief]
