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Cat. No.: HY-107855S4

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DL-Mevalonolactone-¹³C₂

(Synonyms: (±)-Mevalonolactone-¹³C₂; Mevalolactone-¹³C₂)

DL-Mevalonolactone-¹³C₂ ((±)-Mevalonolactone-¹³C₂) is the ¹³C-labeled DL-Mevalonolactone (HY-107855). DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy. DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling^[2][4].

For research use only. We do not sell to patients.

CAS No.: 287111-36-8
Formula: C₄¹³C₂H₁₀O₃
Molecular Weight:132.13

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DL-Mevalonolactone-¹³C₂ Chemical Structure

CAS No.: 287111-36-8

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Biological Activity
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Biological Activity

Description

DL-Mevalonolactone-¹³C₂ ((±)-Mevalonolactone-¹³C₂) is the ¹³C-labeled DL-Mevalonolactone (HY-107855). DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy^[3]. DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling^[2][4].

All Endogenous Metabolite Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 287111-36-8
Unlabeled Cas 674-26-0
Molecular Weight 132.13
Formula C₄¹³C₂H₁₀O₃
SMILES

OC(CCO1)(C)[13CH2][13C]1=O
Synonyms

(±)-Mevalonolactone-¹³C₂; Mevalolactone-¹³C₂
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.