Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
55 Results for "
NRPS
" in MedChemExpress (MCE) Product Catalog:
Products (55)
55 Results for "NRPS" in MCE Product Catalog:
12
12 Publications Verification
Target:
Research Areas:
EG00229 is a neuropilin 1 (NRP1) receptor antagonist. EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 μM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2 .
5
5 Cited Publications
Cat. No.: HY-112151
CAS No.: 2227996-00-9
Target:
Research Areas:
EG01377 is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 μM, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1. EG01377 has antiangiogenic, antimigratory, and antitumor effects .
5
5 Cited Publications
Target:
Research Areas:
EG01377 dihydrochloride is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 μM, and IC50s of 609 nM for both NRP1-a1 and NRP1-b1. EG01377 dihydrochloride has antiangiogenic, antimigratory, and antitumor effects .
3
3 Cited Publications
Target:
Research Areas:
Gln-AMS is an aminoacyl-tRNA synthetases (AARS) inhibitor, which binds the A-domain within the NRPS enzymes.
2
2 Cited Publications
Target:
Research Areas:
Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes .
1
1 Cited Publications
Cat. No.: HY-P1663A
Target:
Research Areas:
ATWLPPR Peptide TFA, a heptapeptide, acts as a selective neuropilin-1 inhibitor, inhibits VEGF165 binding to NRP-1, used in the research of angiogenesis . ATWLPPR Peptide TFA has potential in reducing the early retinal damage caused by diabetes .
Cat. No.: HY-P99386
CAS No.: 1205533-60-3
Synonyms: MNRP-1685A
Target:
Research Areas:
Cat. No.: HY-P3448
CAS No.: 2580154-02-3
Synonyms: CEND-1; iRGD; LSTA1
Target:
Research Areas:
Cat. No.: HY-P10787
CAS No.: 1354801-55-0
Target:
Research Areas:
Cat. No.: HY-P990782
CAS No.: 2566615-11-8
Synonyms: ATYR-1923; KRP-R120
Target:
Research Areas:
Target:
Research Areas:
NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC50 of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research .
Cat. No.: HY-W073762
CAS No.: 2241669-86-1
Target:
Research Areas:
FBnG is a component of non-ribosomal peptide synthetase/polyketide synthase (NRPS/PKS), which is associated with the biosynthesis of fabrubactin (FBN). FBnG can be used for synthesis of AUTAC4 as part of FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 (HY-150408) .
Cat. No.: HY-RS09579
Target:
Research Areas:
NRP1 Human Pre-designed siRNA Set A contains three designed siRNAs for NRP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16529
Target:
Research Areas:
Nrp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nrp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P11286
CAS No.: 632358-46-4
Target:
Research Areas:
Cat. No.: HY-100710
CAS No.: 186692-73-9
Target:
Research Areas:
Epothilone C is a polyketide natural product. Epothilone C is produced by the combined action of one nonribosomal peptide synthetase (NRPS) and nine polyketide synthase (PKS) modules in a multienzyme system. Epothilone C can be used for tumor research .
Cat. No.: HY-P3449
CAS No.: 2522933-44-2
Synonyms: TRS01
Research Areas:
Cat. No.: HY-P3448S
Synonyms: CEND-1-13C6,15N2; iRGD-13C6,15N2; LSTA1-13C6,15N2
Research Areas:
Target:
Research Areas:
NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
