1210945-69-9
1210945-69-9
Chemical Structure
EG00229 trifluoroacetate
- CAS No.: 1210945-69-9
- Formula:C19H20F3N7O7S3
- Molecular Weight:611.60
IUPAC Name: (3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)thiophene-2-carbonyl)-L-arginine compound with 2,2,2-trifluoroacetic acid (1:1)
InChIKey: ZYQBITUOSRZDTG-MERQFXBCSA-N
SMILES: N=C(N)NCCC[C@@H](C(O)=O)NC(C1=C(NS(=O)(C2=CC=CC3=NSN=C32)=O)C=CS1)=O.O=C(O)C(F)(F)F
Biological Activity: EG00229 is a neuropilin 1 (NRP1) receptor antagonist. EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 μM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2[1].
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EG00229 trifluoroacetate | 98.03% | EG00229 is a neuropilin 1 (NRP1) receptor antagonist. EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 μM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2. | ||||||||||||||||||||
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EG00229 trifluoroacetate (Standard) | EG00229 trifluoroacetate (Standard) is the analytical standard of EG00229 (trifluoroacetate) (HY-10799). This product is intended for research and analytical applications. EG00229 is a neuropilin 1 (NRP1) receptor antagonist. EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 μM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2. | |||||||||||||||||||||
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References
