301351-95-1
Chemical Structure
Arg-AMS
- CAS No.: 301351-95-1
- Formula:C16H26N10O7S
- Molecular Weight:502.51
IUPAC Name: ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl (L-arginyl)sulfamate
InChIKey: BPKLMCNLHSJSEL-JVEUSOJLSA-N
SMILES: NC1=C2N=CN([C@@H]3O[C@H](COS(=O)(NC([C@@H](N)CCCNC(N)=N)=O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
Biological Activity: Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes[1].
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Arg-AMS | 98.0% | Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes. | ||||||||||||||||||||
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Keywords