2749438-61-5
Chemical Structure
EG01377 dihydrochloride
- CAS No.: 2749438-61-5
- Formula:C26H32Cl2N6O6S2
- Molecular Weight:659.60
IUPAC Name: (S)-2-(3-((5-(4-(aminomethyl)phenyl)-2,3-dihydrobenzofuran)-7-sulfonamido)thiophene-2-carboxamido)-5-((diaminomethylene)amino)pentanoic acid dihydrochloride
InChIKey: ZYFLTIBQQSYBQT-FJSYBICCSA-N
SMILES: O=S(C1=CC(C2=CC=C(CN)C=C2)=CC3=C1OCC3)(NC4=C(C(N[C@@H](CCC/N=C(N)/N)C(O)=O)=O)SC=C4)=O.Cl.Cl
Biological Activity: EG01377 dihydrochloride is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 μM, and IC50s of 609 nM for both NRP1-a1 and NRP1-b1. EG01377 dihydrochloride has antiangiogenic, antimigratory, and antitumor effects[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EG01377 dihydrochloride | 98.98% | EG01377 dihydrochloride is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 μM, and IC50s of 609 nM for both NRP1-a1 and NRP1-b1. EG01377 dihydrochloride has antiangiogenic, antimigratory, and antitumor effects. | ||||||||||||||||||||
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