24 Results for "

NTS

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "NTS" in MCE Product Catalog:

Cat. No.: HY-130463
CAS No.: 268550-95-4
Purity:  99.23%
Synonyms: PG(16:0/18:1) sodium; 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium
POPG (sodium) is a negatively charged phospholipid. POPG (sodium) affects the interactions of membrane proteins with other molecules by changing the charge characteristics of the lipid environment. POPG (sodium) increases the apparent affinity of Gαq and 1γ1 for activated NTS1. POPG (sodium) can interact with the positive charge of peptides. POPG sodium salt can be used in Parkinson's disease research .
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Cat. No.: HY-P10275
Target:  

Apoptosis

Research Areas:  

Neurological Disease

Tat-NTS peptide is a cell-penetrating peptide with neuroprotective effects. Tat-NTS peptide can specifically inhibit the nuclear translocation of ANXA1 and reduce neuronal apoptosis in ischemic areas. Moreover, Tat-NTS peptide can reduce the volume of cerebral ischemic infarction and can be used in the research of ischemic stroke .
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Cat. No.: HY-137002
CAS No.: 913733-27-4
Research Areas:  

Others

Fmoc-N-Me-Arg(Pbf)-OH is an amino acid derivative containing a guanidinium protecting group on the arginine side chain. Fmoc-N-Me-Arg(Pbf)-OH is used in the synthesis of neurotensin-derived NTS1 ligands for PET imaging .
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Cat. No.: HY-148650
CAS No.: 2691846-93-0
Purity:  99.63%
Target:  

Neurotensin Receptor

Research Areas:  

Neurological Disease

Sortilin antagonist 1 (compound 44) is a sortilin antagonist with an IC50 value of 20 nM for inhibiting Neurotensin (NTS) binds to sortilin. Neurotensin is a sortilin ligand. Sortilin antagonist 1 can be used for the research of neurological disease .
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Cat. No.: HY-P2544
CAS No.: 139026-64-5
Synonyms: JMV438
Target:  

Neurotensin Receptor

Research Areas:  

Neurological Disease

[Lys8, Lys9]-Neurotensin (8-13) (JMV438), a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, with Ki values of 0.33 nM and 0.95 nM for hNTS1 and hNTS2 receptors, respectively .
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Cat. No.: HY-12436
CAS No.: 1623002-61-8
Purity:  98.2%
Target:  

Neurotensin Receptor

Research Areas:  

Neurological Disease

NTRC-824 (Compound 5) is a potent, selective and neurotensin-like nonpeptide neurotensin receptor type 2 (NTS2) antagonist with an IC50 of 38 nM and a Ki of 202 nM. NTRC-824 is >150-fold selectivity for NTS2 over NTS1 (Ki >30 μM) .
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Cat. No.: HY-124831
CAS No.: 1811503-67-9
Target:  

Neurotensin Receptor

Research Areas:  

Neurological Disease

NTRC-844 (compound 8) is a selective antagonist of neurotensin receptor type 2 (NTS2),with the EC50 of 238 nM. NTRC-844 plays an important role in analgesic animal research .
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Cat. No.: HY-137525
CAS No.: 1643879-88-2
Target:  

Neurotensin Receptor

Research Areas:  

Neurological Disease

NTRC-808 is a nonpeptide selective GPCR neurotensin receptor type 2 (NTS2) partial agonist with an EC50 of 14 nM and Ki of 88 nM. NTRC-808 has higher selectivity for NTS2 than for NTS1. NTRC-808 has antipsychotic and analgesic activity .
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Cat. No.: HY-P991147
CAS No.: 2769743-01-1

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Ledostomig is an immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody targeting human netrin-5 (NTS5) and programmed death-1 (PD-1). Ledostomig is promising for research of various cancers .
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Cat. No.: HY-P10767
CAS No.: 2468971-42-6
Target:  

Neurotensin Receptor

Research Areas:  

Neurological Disease

MD01-67 is a selective macrocyclic compound targeting the neurotensin receptor type 2 (NTS2), with Ki of 2.9 nM. MD01-67 exhibits analgesic and tactile hypersensitivity reducing activity in rats acute/persistent/chronic inflammatory pain models .
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Cat. No.: HY-175184
Target:  

Histone Demethylase

Research Areas:  

Infection

LSD1-IN-44 (Compound 19) is a LSD1 inhibitor with an IC50 of 0.02  μM for LSD1-CoREST enzymatic complex. LSD1-IN-44 has significant antischistosomal activity against transformed schistosomula (NTS) and Schistosoma mansoni adult worms while showing a delayed onset of action towards juvenile forms. LSD1-IN-44 has no significant toxicity to human cells. LSD1-IN-44 can be used for schistosomiasis research .
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Cat. No.: HY-RS24084
Research Areas:  

Others

Nts Rat Pre-designed siRNA Set A contains three designed siRNAs for Nts gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-12217
CAS No.: 1612188-96-1
Target:  

Neurotensin Receptor

Research Areas:  

Neurological Disease

NTRC-739 is a selective nonpeptide partial neurotensin receptor type 2 (NTS2) agonist with an EC50 of 12 nM and a Ki of 153 nM. NTRC-739 is 161-fold selective for NTS2 versus NTS1. NTRC-739 can be used for the study of chronic pain research .
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Cat. No.: HY-175185
Target:  

Histone Demethylase

Research Areas:  

Infection

MC3935 is a LSD1 inhibitor with an IC50 of 0.52  μM for LSD1-CoREST enzymatic complex. MC3935 has significant antischistosomal activity against transformed schistosomula (NTS) and Schistosoma mansoni adult worms while showing a delayed onset of action towards juvenile forms. MC3935 has no significant toxicity to human cells. MC3935 can be used for schistosomiasis research .
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Cat. No.: HY-P2025
CAS No.: 113137-57-8
Research Areas:  

Neurological Disease

JMV 236 is a cholecystokinin antagonist with appetite-suppressing activity. JMV 236 affects the regulation of food intake through the interaction of the intestinal endogenous peptide PrRP and the CCK1 receptor. The administration of JMV 236 activates PrRP neurons located in the NTS, thereby enhancing its appetite-suppressing effect. JMV 236 has significant effects on areas of the central nervous system associated with food intake, especially during states of starvation .
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Cat. No.: HY-RS09637
Research Areas:  

Others

NTS Human Pre-designed siRNA Set A contains three designed siRNAs for NTS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17624
Research Areas:  

Others

Nts Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nts gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P73743
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Neurotensin; neuromedin N; NmN-125; NmN; NTS
Species:  
Source:  
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Cat. No.: HY-P11594
Target:  

Neurotensin Receptor

Research Areas:  

Cancer

JMV 7490 is a highly potent and highly hydrophilic neurotensin receptor NTS1 probe that can be successfully labeled with 68Ga and 111In. JMV 7490 acts as an efflux inhibitor to reduce its efflux in NTS1-positive cancer cells; it also serves as an internalization inducer and is efficiently and continuously internalized by NTS1-positive cancer cells. 111In-radiolabeled JMV 7490 shows persistent uptake in NTS1-positive xenografts in nude mice, but no significant uptake in NTS1-negative xenografts. JMV 7490 can be used for in vivo tracer applications of NTS1-positive tumors and supports related research on colorectal cancer .
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Cat. No.: HY-W574030
CAS No.: 126727-03-5
Target:  

Neurotensin Receptor

Research Areas:  

Neurological Disease

Fmoc-DL-Leu-OH acts as a partial agonist of the neurotensin NTS1 receptor (NTS1R) with an EC50 of 215.50 μM. Fmoc-DL-Leu-OH triggers intracellular calcium mobilization, and its activity is blocked by selective NTS1R antagonists. Fmoc-DL-Leu-OH can be used in the research of schizophrenia .
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