268550-95-4
Chemical Structure
POPG sodium
Synonym(s): PG(16:0/18:1) sodium; 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium
- CAS No.: 268550-95-4
- Formula:C40H76NaO10P
- Molecular Weight:770.99
IUPAC Name: sodium 2,3-dihydroxypropyl ((R)-2-(oleoyloxy)-3-(palmitoyloxy)propyl) phosphate
InChIKey: FJXDNGDRHUDFST-XQYKCTAGSA-M
SMILES: CCCCCCCC/C=C\CCCCCCCC(O[C@@H](COP(OCC(O)CO)(O[Na])=O)COC(CCCCCCCCCCCCCCC)=O)=O
Biological Activity: POPG (sodium) is a negatively charged phospholipid. POPG (sodium) affects the interactions of membrane proteins with other molecules by changing the charge characteristics of the lipid environment. POPG (sodium) increases the apparent affinity of Gαq and Gβ1γ1 for activated NTS1. POPG (sodium) can interact with the positive charge of peptides. POPG sodium salt can be used in Parkinson's disease research[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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POPG sodium | 99.23% | POPG (sodium) is a negatively charged phospholipid. POPG (sodium) affects the interactions of membrane proteins with other molecules by changing the charge characteristics of the lipid environment. POPG (sodium) increases the apparent affinity of Gαq and Gβ1γ1 for activated NTS1. POPG (sodium) can interact with the positive charge of peptides. POPG sodium salt can be used in Parkinson's disease research. | ||||||||||||||||||||
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16:0-18:1 PG-d31 | 99% | 16:0-18:1 PG-d31 is deuterium labeled 16:0-18:1 PG. | ||||||||||||||||||||
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POPG-d62 | POPG-d62 (PG(16:0/18:1)-d62) is the deuterium labeled POPG (HY-142991). POPG sodium salt is a negatively charged phospholipid. POPG sodium salt affects the interactions of membrane proteins with other molecules by changing the charge characteristics of the lipid environment. POPG sodium salt increases the apparent affinity of Gαq and Gβ1γ1 for activated NTS1. POPG sodium salt can interact with the positive charge of peptides. POPG sodium salt can be used in Parkinson's disease research. | |||||||||||||||||||||
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- [1]. Kim MR, et al. Co-Encapsulation and Co-Delivery of Peptide Drugs via Polymeric Nanoparticles. Polymers (Basel). 2019;11(2):288. Published 2019 Feb 8. [Content Brief]
- [2]. Inagaki S, et al. Modulation of the interaction between neurotensin receptor NTS1 and Gq protein by lipid. J Mol Biol. 2012 Mar 16;417(1-2):95-111. [Content Brief]
- [3]. Zhao L, et al. Molecular Dynamics Simulations of Human Antimicrobial Peptide LL-37 in Model POPC and POPG Lipid Bilayers. Int J Mol Sci. 2018 Apr 13;19(4):1186. [Content Brief]
- [4]. Agrawal N, et al. Investigating the Effects of the POPC-POPG Lipid Bilayer Composition on PAP248-286 Binding Using CG Molecular Dynamics Simulations. J Phys Chem B. 2023 Oct 26;127(42):9095-9101. [Content Brief]
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