Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
PD-L1 mAb
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "PD-L1 mAb" in MCE Product Catalog:
11
11 Publications Verification
Cat. No.: HY-108730
CAS No.: 1537032-82-8
Synonyms: Anti-Human PD-L1, Human Antibody; MSB 0010718C; MSB0010718C
Target:
Research Areas:
11
11 Publications Verification
Target:
Research Areas:
4
Target:
Research Areas:
2
Target:
Research Areas:
Cat. No.: HY-P99114
CAS No.: 2256084-03-2
Target:
Research Areas:
Cat. No.: HY-P99499
CAS No.: 2050478-92-5
Synonyms: JNJ 63723283; JNJ 3283
Research Areas:
Cat. No.: HY-P99610
CAS No.: 2249882-54-8
Synonyms: BI-754091
Target:
Research Areas:
Cat. No.: HY-P99633
CAS No.: 2342597-81-1
Synonyms: BGB-A333
Target:
Research Areas:
Cat. No.: HY-P99100A
CAS No.: 2556646-63-8
Synonyms: CLT-002 (Powder)
Target:
Research Areas:
Cat. No.: HY-P991356
Synonyms: LAE-005
Target:
Research Areas:
Cat. No.: HY-P991353
Target:
Research Areas:
Cat. No.: HY-P991355
Target:
Research Areas:
Cat. No.: HY-P991357
Target:
Research Areas:
Cat. No.: HY-P991354
Target:
Research Areas:
Cat. No.: HY-179372
CAS No.: 2982893-14-9
Target:
Research Areas:
Tubulin polymerization-IN-84 inhibits tubulin polymerization by targeting the colchicine-binding pocket, with anIC50 = 10.9 μM. Tubulin polymerization-IN-84 shows antiproliferative activity against Jurkat, B16-F10, HCT116, and MDA-MB-231 cells (IC50 = 60 nM, 380 nM, 138 nM, and 1.054 μM). Tubulin polymerization-IN-84 induces G2/M-phase arrest and apoptosis in B16-F10 cells. Tubulin polymerization-IN-84 suppresses tumor growth in a B16-F10 melanoma model and potentiates anti-tumor immunity in combination with a PD-L1 mAb for the research of T-cell acute lymphoblastic leukemia, melanoma, colon cancer, and breast cancer.
Cat. No.: HY-179593
Target:
Research Areas:
GM47-1, a naphthalene scaffold derivative, is a potent mycolic acid transporter MmpL3 inhibitor exhibiting potent bactericidal activity against Mycobacterium abscessus (Mabs) with an MIC50 of 2.1 µM. GM47-1 targets MmpL3, disrupts cell wall integrity, and induces ATP leakage and uncouples respiration. GM47-1 can be used for Mycobacterium abscessus pulmonary disease (Mabs-PD) research .
Cat. No.: HY-L031
820 compounds
Immuno-Oncology is a type of immunotherapy that has the specific purpose of treating cancer. It works by stimulating our immune system to fight back. Normally, our immune system is able to destroy cancer cells in our body, however sometimes cancer cells can adapt and mutate, effectively hiding from our immune system. This is when tumors can develop and become a threat to our health. Immuno-oncology involves mobilizing lymphocytes to recognize and eliminate cancer cells using the body’s immune system. There are several immuno-oncology treatments available, including Immune cell therapy (CAR-T), monoclonal antibodies (mABs) and checkpoint inhibitors, cytokines and cancer vaccines.
MCE Small Molecule Immuno-Oncology Compound Library offers 820 bioactive tumor immunology compounds that target some important checkpoints such as PD1/PD-L1, CXCR, Sting, IDO, TLR, etc. This library is a useful tool for Immuno-oncology research.
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
