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Results for "

PUFA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Biochemical Assay Reagents (1) ClpP (1) Drug Derivative (1) Drug Intermediate (2) Drug Metabolite (2) Endogenous Metabolite (19) Environmental Pollutants (2) Histone Demethylase (6) Isotope-Labeled Compounds (7) Lipocalin Family (1) Lipoxygenase (1) Melatonin Receptor (2) Potassium Channel (1) Prostaglandin Receptor (1) Reference Standards (3) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (12) Cardiovascular Disease (10) Inflammation/Immunology (2) Metabolic Disease (17) Neurological Disease (5)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0729

Linoleic acid 20+ Cited Publications	Environmental Pollutants Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Cancer
Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-B0660

Eicosapentaenoic Acid Maximum Cited Publications 30 Publications Verification EPA; Timnodonic acid	Endogenous Metabolite Histone Demethylase	Neurological Disease Cancer
Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .

HY-N0729S2

Linoleic acid-13C18	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Linoleic acid- ¹³C₁₈ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-21268

Methyl linolenate 1 Publications Verification Linolenic acid methyl ester	Environmental Pollutants Melatonin Receptor	Metabolic Disease
Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC₅₀ of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids .

HY-172199

THX6	ClpP	Cancer
THX6 is an hClpP activator with an EC₅₀ of 1.18 μM. THX6 improves off-target profile with no affinity for hD2R and only weak affinity for hD3R (K_i = 51.1 µM) in HEK293 cells. THX6 shows good cytotoxicity in ONC201-resistant cells with an IC₅₀ of 0.13 μM. THX6 changes the levels of fatty acids (PUFAs, MUFAs, and SFAs) in DIPG cells. THX6 decreases the level of proteins involved in oxidative phosphorylation, biogenesis, and mitophagy proteins, thereby resulting in a global collapse of mitochondrial integrity and function. THX6 can be used for diffuse intrinsic pontine glioma research .

HY-N0729S

Linoleic acid-d4	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Linoleic Acid-d₄ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-N0729R

Linoleic acid (Standard) 20+ Cited Publications	Reference Standards Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Cancer
Linoleic acid (Standard) is the analytical standard of Linoleic acid (HY-N0729). This product is intended for research and analytical applications. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-B0660R

Eicosapentaenoic Acid (Standard) EPA (Standard); Timnodonic acid (Standard)	Reference Standards Endogenous Metabolite Histone Demethylase	Neurological Disease Cancer
Eicosapentaenoic Acid (Standard) is the analytical standard of Eicosapentaenoic Acid. This product is intended for research and analytical applications. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .

HY-N7140R

Gamma-Linolenic acid (Standard) 5+ Cited Publications γ-Linolenic acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Gamma-Linolenic acid (Standard) is the analytical standard of Gamma-Linolenic acid. This product is intended for research and analytical applications. Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .

HY-158812

Eicosapentaenoyl-L-carnitine chloride	Drug Derivative	Metabolic Disease
Eicosapentaenoyl-L-carnitine chloride is a long-chain acylcarnitine composed of Eicosapentaenoic Acid (HY-B0660) and L-Carnitine (HY-B0399). The levels of Eicosapentaenoyl-L-carnitine chloride are increased in the eyes of mice fed a diet high in n-3/n-6 polyunsaturated fatty acids (PUFAs) in a mouse model of myopia induced by out-of-focus lenses .

HY-N0729S4

Linoleic acid-d5	Isotope-Labeled Compounds	Cardiovascular Disease Metabolic Disease
Linoleic Acid-d₅ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-N0729S3

Linoleic acid-13C1	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Linoleic acid- ¹³C₁ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-138148

13(S)-HPOTrE(γ)	Lipoxygenase	Inflammation/Immunology
13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid. Further action of soybean LO-1 converts 13(S)-HpOTrE(γ) to all four isomers of 6,13-DiHOTrE.2 At concentrations greater than 100 μM, 13(S)-HpOTrE(γ) inhibits the activity of soybean LO-1.

HY-W011269

Eicosapentaenoic Acid sodium Maximum Cited Publications 30 Publications Verification EPA sodium; Timnodonic acid sodium	Endogenous Metabolite Histone Demethylase	Cardiovascular Disease Metabolic Disease Cancer
Eicosapentaenoic Acid (EPA)sodium is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid sodium exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid sodium activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid sodium can promote relaxation of vascular smooth muscle cells and vasodilation .

HY-134544

Calendic acid	Apoptosis	Cancer
Calendic acid (8(E),10(E),12(Z)-Octadecatrienoic acid) is a conjugated polyunsaturated fatty acid (PUFA) that can be isolated from C. officinalis seed oil. Calendic acid has anticancer activity .

HY-147335

6,9,12,15-Hexadecatetraenoic acid-ethyl ester	Endogenous Metabolite	Cardiovascular Disease
6,9,12,15-Hexadecatetraenoic acid-ethyl ester is an orally active n-1PUFA. 6,9,12,15-Hexadecatetraenoic acid-ethyl ester intake can reduce plasma triglyceride content in mice .

HY-124303

4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic acid	Biochemical Assay Reagents	Metabolic Disease
4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic acid is a polyunsaturated fatty acid (PUFA).

HY-N0729S5

Linoleic acid-d2 Deulinoleic acid	Endogenous Metabolite	Metabolic Disease
Linoleic Acid-d₂ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-N0729S1

Linoleic acid-d11	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Linoleic acid-d₁₁ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-141635

cis-11,14-Eicosadienoic acid methyl ester	Endogenous Metabolite	Metabolic Disease
cis-11,14-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5’-monophosphate dehydrogenase (Ki=3.1 μM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki=3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance.3 Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators.

HY-B0660S1

Eicosapentaenoic acid 1,2,3,4,5-13C5 EPA 1,2,3,4,5-13C, FA 20:5-¹³C₅	Isotope-Labeled Compounds Endogenous Metabolite Histone Demethylase	Neurological Disease Cancer
Eicosapentaenoic acid 1,2,3,4,5- ¹³C₅ (EPA 1,2,3,4,5- ¹³C, FA 20:5- ¹³C₅) is ¹³C labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .

HY-121520

Docosahexaenoyl glycine	Potassium Channel Endogenous Metabolite	Cardiovascular Disease
Docosahexaenoyl glycine is a PUFA analogue. Docosahexaenoyl glycine has activating effects on IKs channels and restore the function of IKs channels with LQT1 mutation .

HY-RS11463

PUM3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PUM3 Human Pre-designed siRNA Set A contains three designed siRNAs for PUM3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PUM3 Human Pre-designed siRNA Set A PUM3 Human Pre-designed siRNA Set A

HY-165078

(±)11(12)-EpETE (±)11,12-EEQ; (±)11,12-Epoxyeicosatetraenoic acid	Endogenous Metabolite	Others
(±)11(12)-EpETE ((±)11,12-EEQ) is an EPA hydroxyl product. EPA is a major component of Omega-3 polyunsaturated fatty acids (PUFAs) .

HY-175079

(±)17(18)-DiHETE	Drug Metabolite	Metabolic Disease
(±)17(18)-DiHETE is an oxidized lipid and a metabolite of Eicosapentaenoic Acid (HY-B0660), an orally active omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA) .

HY-134511

15(S)-HpEPE	Prostaglandin Receptor	Inflammation/Immunology Cancer
15(S)-HpEPE is a product of lipoxygenase hydrolysis of unsaturated fatty acids (PUFA) and is a potential inhibitor of prostaglandin H synthase 2 (PGHS-2). 15(S)-HpEPE can downregulate the expression of PGHS-2 .

HY-21268S

Methyl linolenate-13C18 Linolenic acid methyl ester-¹³C₁₈	Isotope-Labeled Compounds	Others
Methyl linolenate- ¹³C₁₈ is the ¹³C labeled Methyl linolenate . Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids . The IC₅₀ is 60 uM .

HY-176160

Jacaric acid methyl ester Methyl jacarate; SFE 19:3	Apoptosis	Cancer
Jacaric acid methyl ester is a methyl ester form of the conjugated PUFA jacaric acid. Jacaric acid can induce apoptosis selectively in human prostate cancer cells. Jacaric acid induces concentration- and time-dependent LNCaP cell death. Jacaric acid methyl ester can be studied in anticancer research .

HY-175098

(±)14(15)-DiHETE	Drug Metabolite	Metabolic Disease
(±)14(15)-DiHETE, an oxylipin, is a metabolite of Eicosapentaenoic Acid (HY-B0660). Eicosapentaenoic Acid is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA) .

HY-W718383

7(Z),10(Z),13(Z)-Hexadecatrienoic acid Roughanic acid	Drug Intermediate	Others
7(Z),10(Z),13(Z)-Hexadecatrienoic acid (Roughanic acid) is an ω-3 polyunsaturated fatty acid (PUFA) that can be found in the leaves of S. olusatrum. 7(Z),10(Z),13(Z)-Hexadecatrienoic acid is an intermediate in the biosynthesis of jasmonic acid .

HY-W744883

Methyl-d3 Linolenate	Isotope-Labeled Compounds Melatonin Receptor	Metabolic Disease
Methyl-d₃ Linolenate is the deuterium labeled Methyl linolenate (HY-21268). Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC₅₀ of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids .

HY-158575

all-cis-14,17,20,23,26,29-Dotriacontahexaenol 14(Z),17(Z),20(Z),23(Z),26(Z),29(Z)-Dotriacontahexaenol	Drug Intermediate	Others
all-cis-14,17,20,23,26,29-Dotriacontahexaenol (14(Z),17(Z),20(Z),23(Z),26(Z),29(Z)-Dotriacontahexaenol) is a long-chain fatty alcohol. It is an intermediate in the synthesis of the very long-chain PUFA all-cis-14,17,20,23,26,29-dotriacontahexaenoic acid .

HY-B0660A

Eicosapentaenoic acid metformin EPA metformin; Timnodonic acid metformin	Endogenous Metabolite Histone Demethylase	Neurological Disease Cancer
Eicosapentaenoic Acid (EPA) metformin is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic acid metformin exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). EEicosapentaenoic acid metformin activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic acid metformin can promote relaxation of vascular smooth muscle cells and vasodilation .

HY-W339816

(S,R)-Bis(monomyristoylglycero)phosphate ammonium	Lipocalin Family Endogenous Metabolite	Others
(S,R)-Bis(monomyristoylglycero)phosphate ammonium actively contributes to cargo sorting by promoting the degradation and sorting of lipids, and it plays a critical role in the sorting of polyunsaturated fatty acids (PUFAs) within acidic organelles. This phospholipid features two phosphate-linked glycerol molecules arranged in a unique sn-1 glycerophospho-sn-1′ glycerol stereoconformation, with each glycerol molecule esterified to a myristic acid. Typically, it is found in the intraluminal vesicles (ILVs) of late endosomes and lysosomes.

HY-B0660S2

Eicosapentaenoic acid-d10 EPA-d₁₀; Timnodonic acid-d₁₀	Isotope-Labeled Compounds Endogenous Metabolite Histone Demethylase	Neurological Disease Cancer
Eicosapentaenoic acid-d₁₀ (EPA-d₁₀) is the deuterium labeled Eicosapentaenoic acid (HY-B0660). Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .

Docosahexaenoyl glycine	Potassium Channel Endogenous Metabolite	Cardiovascular Disease
Docosahexaenoyl glycine is a PUFA analogue. Docosahexaenoyl glycine has activating effects on IKs channels and restore the function of IKs channels with LQT1 mutation .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0729

Linoleic acid 20+ Cited Publications	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Biological Pesticide Research Source Classification Agricultural Research	Environmental Pollutants Endogenous Metabolite
Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-B0660

Eicosapentaenoic Acid Maximum Cited Publications 30 Publications Verification EPA; Timnodonic acid	Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite Histone Demethylase
Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .

HY-21268

Methyl linolenate 1 Publications Verification Linolenic acid methyl ester	Structural Classification other families Classification of Application Fields Other Diseases Plants Disease Research Fields Lipid Source Classification	Environmental Pollutants Melatonin Receptor
Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC₅₀ of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids .

HY-N0729R

Linoleic acid (Standard) 20+ Cited Publications	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Biological Pesticide Research Source Classification Agricultural Research	Reference Standards Endogenous Metabolite
Linoleic acid (Standard) is the analytical standard of Linoleic acid (HY-N0729). This product is intended for research and analytical applications. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-B0660R

Eicosapentaenoic Acid (Standard) EPA (Standard); Timnodonic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Histone Demethylase
Eicosapentaenoic Acid (Standard) is the analytical standard of Eicosapentaenoic Acid. This product is intended for research and analytical applications. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .

HY-N7140R

Gamma-Linolenic acid (Standard) 5+ Cited Publications γ-Linolenic acid (Standard)	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Labiatae Disease markers Endocrine diseases Metabolic Disease Tadehagi triquetrum (L.) Ohashi Plants Endogenous metabolite Disease Research Fields Source Classification	Reference Standards Endogenous Metabolite
Gamma-Linolenic acid (Standard) is the analytical standard of Gamma-Linolenic acid. This product is intended for research and analytical applications. Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .

HY-W011269

Eicosapentaenoic Acid sodium Maximum Cited Publications 30 Publications Verification EPA sodium; Timnodonic acid sodium	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Histone Demethylase
Eicosapentaenoic Acid (EPA)sodium is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid sodium exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid sodium activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid sodium can promote relaxation of vascular smooth muscle cells and vasodilation .

HY-134544

Calendic acid	Ketones, Aldehydes, Acids Plants Compositae Millettia usaramensis Taub. Source Classification	Apoptosis
Calendic acid (8(E),10(E),12(Z)-Octadecatrienoic acid) is a conjugated polyunsaturated fatty acid (PUFA) that can be isolated from C. officinalis seed oil. Calendic acid has anticancer activity .

HY-121520

Docosahexaenoyl glycine	Cardiovascular Disease Structural Classification Alkaloids Classification of Application Fields Ketones, Aldehydes, Acids Other Alkaloids Endogenous metabolite Disease Research Fields Source Classification	Potassium Channel Endogenous Metabolite
Docosahexaenoyl glycine is a PUFA analogue. Docosahexaenoyl glycine has activating effects on IKs channels and restore the function of IKs channels with LQT1 mutation .

Cat. No.	Product Name	Chemical Structure

HY-N0729S2

Linoleic acid-13C18

Linoleic acid- ¹³C₁₈ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-N0729S

Linoleic acid-d4

Linoleic Acid-d₄ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-N0729S4

Linoleic acid-d5

Linoleic Acid-d₅ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-N0729S3

Linoleic acid-13C1

Linoleic acid- ¹³C₁ is the ¹³C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-N0729S5

Linoleic acid-d2

Linoleic Acid-d₂ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-N0729S1

Linoleic acid-d11

Linoleic acid-d₁₁ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

HY-B0660S1

Eicosapentaenoic acid 1,2,3,4,5-13C5

Eicosapentaenoic acid 1,2,3,4,5- ¹³C₅ (EPA 1,2,3,4,5- ¹³C, FA 20:5- ¹³C₅) is ¹³C labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .

HY-21268S

Methyl linolenate-13C18
Methyl linolenate- ¹³C₁₈ is the ¹³C labeled Methyl linolenate . Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids . The IC₅₀ is 60 uM .

HY-W744883

Methyl-d3 Linolenate
Methyl-d₃ Linolenate is the deuterium labeled Methyl linolenate (HY-21268). Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC₅₀ of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids .

HY-B0660S2

Eicosapentaenoic acid-d10

Eicosapentaenoic acid-d₁₀ (EPA-d₁₀) is the deuterium labeled Eicosapentaenoic acid (HY-B0660). Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .

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