5204-87-5
5204-87-5
Chemical Structure
Calendic acid
- CAS No.: 5204-87-5
- Formula:C18H30O2
- Molecular Weight:278.43
IUPAC Name: (8E,10E,12Z)-octadeca-8,10,12-trienoic acid
InChIKey: DQGMPXYVZZCNDQ-KBPWROHVSA-N
SMILES: CCCCC/C=C\C=C\C=C\CCCCCCC(O)=O
Biological Activity: Calendic acid (8(E),10(E),12(Z)-Octadecatrienoic acid) is a conjugated polyunsaturated fatty acid (PUFA) that can be isolated from C. officinalis seed oil. Calendic acid has anticancer activity[1][2][3].
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Calendic acid | Calendic acid (8(E),10(E),12(Z)-Octadecatrienoic acid) is a conjugated polyunsaturated fatty acid (PUFA) that can be isolated from C. officinalis seed oil. Calendic acid has anticancer activity. | |||||||||||||||||||||
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References
- [1]. Crombie L, et al. The biosynthesis of calendic acid, octadeca-(8 E, 10 E, 12 Z)-trienoic, acid, by developing marigold seeds: origins of (E, E, Z) and (Z, E, Z) conjugated triene acids in higher plants. Journal of the Chemical Society, Perkin Transactions 1, 1985: 2425-2434.
- [2]. Yasui Y, et al. Growth inhibition and apoptosis induction by all-trans-conjugated linolenic acids on human colon cancer cells. Anticancer Res. 2006 May-Jun;26(3A):1855-60. [Content Brief]
- [3]. Shinohara N, et al. jacaric acid, a linolenic acid isomer with a conjugated triene system, reduces stearoyl-CoA desaturase expression in liver of mice. J Oleo Sci. 2012;61(8):433-41. [Content Brief]
