301-00-8
Chemical Structure
Methyl linolenate
Synonym(s): Linolenic acid methyl ester
- CAS No.: 301-00-8
- Formula:C19H32O2
- Molecular Weight:292.46
IUPAC Name: methyl (9Z,12Z,15Z)-octadeca-9,12,15-trienoate
InChIKey: DVWSXZIHSUZZKJ-YSTUJMKBSA-N
SMILES: CC/C=C\C/C=C\C/C=C\CCCCCCCC(OC)=O
Biological Activity: Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC50 of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids[1][2][3][4].
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Methyl linolenate | 99.46% | Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC50 of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids. | ||||||||||||||||||||
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Methyl linolenate-13C18 | Methyl linolenate-13C18 is the 13C labeled Methyl linolenate. Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids. The IC50 is 60 uM. | |||||||||||||||||||||
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Methyl linolenate-13C17 | Methyl linolenate-13C17 is an isotope-labeled fatty acid ester. | |||||||||||||||||||||
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Methyl-d3 Linolenate | Methyl-d3 Linolenate is the deuterium labeled Methyl linolenate (HY-21268). Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC50 of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids. | |||||||||||||||||||||
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- [1]. Huh S et al. Melanogenesis inhibitory effect of fatty acid alkyl esters isolated from Oxalis triangularis. Biol Pharm Bull, 2010, 33(7):1242-5.
- [2]. Li X et al. Benchmark Calculations for Bond Dissociation Enthalpies of Unsaturated Methyl Esters and the Bond Dissociation Enthalpies of Methyl Linolenate. J Phys Chem A, 2016, Jun 16, 120(23):4025-36 [Content Brief]
- [3]. Huh S, et al. Melanogenesis inhibitory effect of fatty acid alkyl esters isolated from Oxalis triangularis. Biol Pharm Bull. 2010;33(7):1242-5. [Content Brief]
- [4]. Ko GA, et al. Sageretia thea fruit extracts rich in methyl linoleate and methyl linolenate downregulate melanogenesis via the Akt/GSK3β signaling pathway. Nutr Res Pract. 2018 Feb;12(1):3-12. [Content Brief]