15444 Results for "

Protein A

" in MedChemExpress (MCE) Product Catalog:
Products (15444)

15444 Results for "Protein A" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-NP006
CAS No.: 308083-69-4
Synonyms: SPA
Protein A (SPA) is an immunoglobulin (Ig)-binding protein that exists on the bacterial surface and can be freely secreted into the extracellular environment. Protein A blocks opsonophagocytosis and induces B cell apoptosis in vitro by binding to the Fc region of antibodies and the Fab region of B cell receptors. Protein A can form toxic immune complexes with IgG, thereby inducing leukocyte necrosis. Protein A contributes to the virulence expression of Staphylococcus aureus. Protein A triggers allergic reactions in IgG-pretreated mouse models. Protein A can be used in studies related to immune system diseases .
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2066
2066 Publications Verification
Cat. No.: HY-K0010

MCE Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO) is a blend of 6 pan-protease inhibitors for protection of protein integrity.The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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1441
1441 Cited Publications
Cat. No.: HY-10219
CAS No.: 53123-88-9
Purity:  99.94%
Synonyms: Sirolimus; AY-22989; NSC 226080
Rapamycin (Sirolimus; AY 22989) is a potent and specific blood-brain barrier-transmissible mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin is a molecular glue that binds FKBP12 and mTOR proteins together, thereby inhibiting mTOR kinase activity. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .
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1391
1391 Cited Publications
Cat. No.: HY-K0202

MCE Protein A/G Magnetic Beads provide a fast and convenient method for Immunoprecipitation, Co-Immunoprecipitation and Chromatin Immunoprecipitation. The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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885
885 Cited Publications
Cat. No.: HY-100558
CAS No.: 88899-55-2
Purity:  99.95%
Synonyms: BafA1
Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H +-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis .
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825
825 Cited Publications
Cat. No.: HY-18739
CAS No.: 16561-29-8
Synonyms: PMA; TPA; Phorbol myristate acetate
Phorbol 12-myristate 13-acetate (PMA; TPA; Phorbol myristate acetate), a phorbol ester, is a dual SphK and protein kinase C (PKC) activator . Phorbol 12-myristate 13-acetate is a NF-κB activator. Phorbol 12-myristate 13-acetate induces differentiation in THP-1 cells (Validated by MedChemExpress) .
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722
722 Cited Publications
Cat. No.: HY-K0021

Phosphatase Inhibitor Cocktail I (100× in DMSO) is a blend of 2 phosphatase inhibitors that can effectively inhibit alkaline phosphatases and serine/threonine phosphatases. It is used to maintain the phosphorylation status of proteins.The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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551
551 Cited Publications
Cat. No.: HY-100218A
CAS No.: 1219810-16-8
Purity:  99.90%
Synonyms: (1S,3R)-RSL3
RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells .
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479
479 Cited Publications
Cat. No.: HY-K0022

Phosphatase Inhibitor Cocktail Ⅱ (100× in ddH2O) is a blend of 5 phosphatase inhibitors that can broadly inhibit acid phosphatases, alkaline phosphatases, and protein tyrosine phosphatases (PTPs).The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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436
436 Cited Publications
Cat. No.: HY-B1743
CAS No.: 53-79-2
Synonyms: CL13900
Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.
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436
436 Cited Publications
Cat. No.: HY-B1743A
CAS No.: 58-58-2
Synonyms: CL13900 dihydrochloride
Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .
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346
346 Cited Publications
Cat. No.: HY-15886
CAS No.: 338967-87-6
Purity:  99.96%
Synonyms: Mitochondrial division inhibitor 1
Research Areas:  

Cancer

Mdivi-1 is a selective dynamin-related protein 1 (Drp1) inhibitor. Mdivi-1 is a mitochondrial division/mitophagy inhibitor.
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261
261 Cited Publications
Cat. No.: HY-P0175
CAS No.: 1236188-16-1
Synonyms: 740YPDGFR; PDGFR 740Y-P
Target:  

PI3K Autophagy

Research Areas:  

Cancer

740 Y-P (740YPDGFR; PDGFR 740Y-P) is a potent and cell-permeable PI3K activator. 740 Y-P readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone .
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258
258 Cited Publications
Cat. No.: HY-K0011

MCE Protease Inhibitor Cocktail, mini-Tablet (EDTA-Free) is a blend of 5 pan-protease inhibitors for protection of protein integrity. The 25 pcs is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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253
253 Cited Publications
Cat. No.: HY-K0207

MCE Anti-Flag Magnetic Beads are used for immunoprecipitation (IP) of specific Flag-tagged (DYKDDDDK) proteins expressed in bacterial and mammalian cells and in vitro expression systems, and also suitable for Co-immunoprecipitation and purification of Flag-tagged protein. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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244
244 Cited Publications
Cat. No.: HY-K0023

Phosphatase Inhibitor Cocktail Ⅲ (100× in DMSO) is a mixture of multiple phosphatase inhibitors that effectively inhibit serine/threonine phosphatases and alkaline phosphatases, and is used to preserve the phosphorylation status of proteins.The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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227
227 Cited Publications
Cat. No.: HY-15141
CAS No.: 62996-74-1
Purity:  99.52%
Synonyms: Antibiotic AM-2282; STS; AM-2282
Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer .
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226
226 Cited Publications
Cat. No.: HY-10484
CAS No.: 1160295-21-5
Purity:  98.58%
Synonyms: MLN4924 hydrochloride
Research Areas:  

Cancer

Pevonedistat (MLN4924) hydrochloride is a potent and selective NEDD8-activating enzyme (NAE) inhibitor, with an IC50 of 4.7 nM. Pevonedistat hydrochloride induces the deregulation of S-phase DNA synthesis, thereby disrupting protein turnover mediated by cullin-RING ligase, leading to apoptosis of human tumor cells. Pevonedistat hydrochloride suppresses the growth of human tumour xenografts in mice .
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226
226 Cited Publications
Cat. No.: HY-70062
CAS No.: 905579-51-3
Synonyms: MLN4924
Research Areas:  

Cancer

Pevonedistat (MLN4924) is a potent and selective NEDD8-activating enzyme (NAE) inhibitor with an IC50 of 4.7 nM. Pevonedistat induces the deregulation of S-phase DNA synthesis, thereby disrupting protein turnover mediated by cullin-RING ligase, leading to apoptosis of human tumor cells. Pevonedistat suppresses the growth of human tumour xenografts in mice .
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223
223 Cited Publications
Cat. No.: HY-K0208

MCE Streptavidin Magnetic Beads provide a fast and convenient method for numerous applications, including purification of proteins and nucleic acids, protein interaction studies, immunoprecipitation, immunoassays, pull-down and cell isolation. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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