58-58-2
58-58-2
Chemical Structure
Puromycin dihydrochloride
Synonym(s): CL13900 dihydrochloride
- CAS No.: 58-58-2
- Formula:C22H31Cl2N7O5
- Molecular Weight:544.43
IUPAC Name: (S)-2-amino-N-((2S,3S,4R,5R)-5-(6-(dimethylamino)-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)-3-(4-methoxyphenyl)propanamide dihydrochloride
InChIKey: MKSVFGKWZLUTTO-FZFAUISWSA-N
SMILES: OC[C@@H]1[C@@H](NC([C@@H](N)CC2=CC=C(OC)C=C2)=O)[C@H]([C@H](N3C=NC4=C3N=CN=C4N(C)C)O1)O.[H]Cl.[H]Cl
Biological Activity: Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Puromycin dihydrochloride | 99.93% | Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis. | ||||||||||||||||||||
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Puromycin dihydrochloride (Standard) | 99.84% | Puromycin (dihydrochloride) (Standard) is the analytical standard of Puromycin (dihydrochloride). This product is intended for research and analytical applications. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis. | ||||||||||||||||||||
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Puromycin-d3 dihydrochloride | 98.0% | Puromycin-d3 (dihydrochloride) is the deuterium labeled Puromycin dihydrochloride. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis. | ||||||||||||||||||||
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N-Acetylpuromycin | N-Acetylpuromycin is a inactive form of the antibiotic puromycin. N-Acetylpuromycin is the last intermediate of the puromycin antibiotic biosynthetic pathway in Streptomyces alboniger. | |||||||||||||||||||||
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N6-(4-Methoxybenzyl)adenosine | N6-(4-Methoxybenzyl)adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277). | |||||||||||||||||||||
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N-[(3-Methoxyphenyl)methyl]adenosine | N-[(3-Methoxyphenyl)methyl]adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277). | |||||||||||||||||||||
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3’-Azido-3’-deoxy-N6,N6-dimethyladenosine | 3’-Azido-3’-deoxy-N6,N6-dimethyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. 3’-Azido-3’-deoxy-N6,N6-dimethyladenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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2’-Chloro-N6-(4-methoxy)benzyl adenosine | 2’-Chloro-N6-(4-methoxy)benzyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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N6-(4-Methoxybenzyl)-2’-C-methyl adenosine | N6-(4-Methoxybenzyl)-2’-C-methyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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O-Propargyl-Puromycin | 99.71% | O-Propargyl-Puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-Propargyl-Puromycin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Puromycin aminonucleoside | 99.86% | Puromycin aminonucleoside (NSC 3056) is the aminonucleoside portion of the antibiotic puromycin, and used in nephrosis animal models. Puromycin aminonucleoside induces apoptosis. Puromycin aminonucleoside is a reversible inhibitor of dipeptidyl peptidase II and cytosol alanyl aminopeptidase. Puromycin aminonucleoside induces secretion of cell migrasome. | ||||||||||||||||||||
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Puromycin | 99.67% | Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis. | ||||||||||||||||||||
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CNP0296775 | CNP0296775 is an inhibitor of dengue virus methyltransferase (DENV MTase) that has the potential to disrupt the viral replication process. | |||||||||||||||||||||
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