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Results for "

Pyrazolo[1,5-a]pyrimidine

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-78428
    CDK-IN-6

    		CDK Cancer
    CDK-IN-6, a class of pyrazolo[1,5-a]pyrimidine compound, is a CDK inhibitor with anticancer activities .
    CDK-IN-6
  • HY-W003486
    5,7-Dichloropyrazolo[1,5-a]pyrimidine

    		Phosphodiesterase (PDE) Neurological Disease Cancer
    5,7-Dichloropyrazolo[1,5-a]pyrimidine is a PDE10A inhibitor with a Ki of 24 μM. 5,7-Dichloropyrazolo[1,5-a]pyrimidine serves as a key intermediate in the synthesis of 5,7-disubstituted pyrazolo[1,5-a]pyrimidine derivatives (HIV-1 non-nucleoside reverse transcriptase inhibitors). 5,7-Dichloropyrazolo[1,5-a]pyrimidine can be used for the research of schizophrenia .
    5,7-Dichloropyrazolo[1,5-a]pyrimidine
  • HY-112505
    Efflux inhibitor-1

    		BCRP Cancer
    Efflux inhibitor-1 (compound 2) is a pyrazolo[1,5-a]pyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC50s of 0.45 μM and 2.17 μM, respectively .
    Efflux inhibitor-1
  • HY-130070
    QO-40

    		Potassium Channel Neurological Disease
    QO-40, a pyrazolo[1,5-a]pyrimidine-7(4H)-one (PPO) derivative, is a KCNQ2/KCNQ3 K + channels activator with an EC50 of 6.94 μM. QO-40 stimulated Ca 2+-activated K + current (IK(Ca)) with an EC50 value of 2.3 μM in pituitary GH3 lactotrophs .
    QO-40

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