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Results for "

Pyridyl

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (2) Aminopeptidase (1) Bacterial (4) Biochemical Assay Reagents (5) COX (1) Cytochrome P450 (2) Drug Intermediate (8) Drug Metabolite (2) Endogenous Metabolite (3) Fluorescent Dye (4) Glucocorticoid Receptor (1) Isocitrate Dehydrogenase (IDH) (1) Isotope-Labeled Compounds (4) Liposome (1) MOFs (70) Nucleoside Antimetabolite/Analog (1) Parasite (1) Reference Standards (3) Reverse Transcriptase (1) ROCK (1) Small Interfering RNA (siRNA) (1) TGF-β Receptor (1) TMV (1) Topoisomerase (1) Transketolase (1) Vasopressin Receptor (1)
By Research Areas:	Cancer (6) Endocrinology (2) Infection (4) Inflammation/Immunology (5)
Oligonucleotides:	Nucleoside Analogs (1) Inosine (1) Cationic Lipids (1)

115

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-16339

N3PT 2 Publications Verification N3-Pyridyl thiamine	Transketolase	Cancer
N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor. N3PT is pyrophosphorylated and then binds to transketolase with an K_d value of 22 nM (Apo-TK, transketolase lacking bound thiamine) .

HY-135368

8pyDTZ 3 Publications Verification	Fluorescent Dye	Others
8pyDTZ is a pyridyl diphenylterazine (DTZ) analog and an ATP-independent pyridyl substrate of LumiLuc luciferase. 8pyDTZ exhibits spectrally shifted emission. 8pyDTZ has excellent biocompatibility and superior in vivo sensitivity. 8pyDTZ can be used for in vivo luminescence imaging .

HY-112362

*3-(4-Pyridyl)indole* Rockout; 3-(4-Pyridinyl)-1H-indole; Rho Kinase Inhibitor III, Rockout	ROCK	Inflammation/Immunology
3-(4-Pyridyl)indole (Rockout) is a Rho-kinase (ROCK) inhibitor, with an IC₅₀ of 25 μM. 3-(4-Pyridyl)indole can inhibit blebbing and cause dissolution of actin stress fibers in a wound healing assay .

HY-W017463

*trans-3-(3-Pyridyl)acrylic acid*	Drug Intermediate TMV Isocitrate Dehydrogenase (IDH)	Infection
trans-3-(3-Pyridyl) acrylic acid is an unsaturated carboxylic acid and synthetic building block, which serves as a synthetic precursor of 3-(3-pyridyl) propanoic acid. trans-3-(3-Pyridyl) acrylic acid can be used to prepare dual mutant IDH1/NAMPT inhibitors and PGE₂ antagonist analogs. In addition, trans-3-(3-Pyridyl) acrylic acid exhibits antiviral activity against tobacco mosaic virus (TMV) .

HY-W001990

2-Piperazinopyridine 1-(Pyridin-2-yl)piperazine	Biochemical Assay Reagents	Others
1-(2-Pyridyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W019817

*4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol* NNAL	Endogenous Metabolite	Cancer
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is the main metabolite of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific lung carcinogen. The oxidative metabolic pathway in which NNAL is oxidized to NNK and other products exhibits carcinogenic activity. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol can be used in research on carcinogenic mechanisms related to lung cancer .

HY-W002805

2-Bromoisonicotinic acid 1 Publications Verification	Drug Intermediate	Others
2-Bromoisonicotinic acid is a (hetero)aryl bromide building block and DNA-conjugated headpiece for photochemical C-H heteroarylation in DNA-encoded library synthesis. 2-Bromoisonicotinic acid generates a nucleophilic pyridyl radical intermediate. 2-Bromoisonicotinic acid, when conjugated to DNA, leaves electrophilic handles intact for subsequent library diversification .

HY-164793

TGFBR1-IN-2	TGF-β Receptor Cytochrome P450 Bacterial	Infection
TGFBR1-IN-2 (Compound AQA) is a TGFBR1 inhibitor and an antibacterial agent. TGFBR1-IN-2 is a substrate for cytochrome P450s. TGFBR1-IN-2 contains the pyridyl-6-methyl moiety necessary for Mycobacterium tuberculosis inhibition and has potent inhibitory activity against non-replicating and persistent Mycobacterium tuberculosis .

HY-W003985

*N-Boc-3-(2-pyridyl)-L-alanine*	Amino Acid Derivatives	Others
N-Boc-3-(2-pyridyl)-L-alanine is an alanine derivative .

HY-W004126

2-Iodopyridine 2-Pyridyl iodide	Biochemical Assay Reagents	Others
2-Iodopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W008874

*meso-Tetra(4-pyridyl)porphine*	Topoisomerase	Cancer
meso-Tetra(4-pyridyl)porphine (Compound 10) is a porphyrin derivative. meso-Tetra(4-pyridyl)porphine is a weak inhibitor of human topoisomerase I (Top1) with an EC₅₀ value greater than 50 µM. meso-Tetra(4-pyridyl)porphine can be used in tumor research .

HY-21059

*2-(Pyridyl-2-yl)imidazole* 2-(1H-Imidazol-2-yl)pyridine	MOFs	Others
2-(Pyridyl-2-yl)imidazole (2-(1H-Imidazol-2-yl)pyridine) is a metal-organic framework (MOF).

HY-P4010

*Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin*	Vasopressin Receptor	Others
Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), is a weak agonist at antidiuretic receptor. However, Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin is a potent agonist at pituitary corticotrope receptor .

HY-W075426

5,10,15,20-Tetra(pyridin-3-yl)porphyrin Tetra(3-Pyridyl)porphyrin	MOFs	Others
5,10,15,20-Tetra(pyridin-3-yl)porphyrin (Tetra(3-pyridyl)porphyrin) is a metal-organic framework (MOF).

HY-44072

*7-Chloro-6-fluoro-1-(2-isopropyl-4-methyl-3-pyridyl)pyrido[2,3-d]pyrimidine-2,4-dione*	Drug Intermediate	Others
7-Chloro-6-fluoro-1-(2-isopropyl-4-methyl-3-pyridyl)pyrido[2,3-d]pyrimidine-2,4-dione is a drug intermediate for synthesis of various active compounds.

HY-W009906

*2-(2′-Pyridyl)benzimidazole*	Aminopeptidase	Inflammation/Immunology
2-(2’-Pyridyl)benzimidazole is a potentially tridentate ligand that can form stable complexes with various transition metal ions. 2-(2’-Pyridyl)benzimidazole can be used as an anti-inflammatory agent and an inhibitor of Escherichia coli methionine aminopeptidase .

HY-116232

*2-(3-Pyridyl)-benzimidazole*	Cytochrome P450
2-(3-Pyridyl)-benzimidazole is an Aminopyrine N-Demethylase inhibitor .

HY-W012428

*2-(3-Pyridyl)-4-methyl-thiazole-5-carboxylic acid*	Drug Intermediate	Others
2-(3-Pyridyl)-4-methyl-thiazole-5-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.

HY-W089929

2-(3-(Pyridin-4-yl)-1H-1,2,4-triazol-5-yl)pyridine 3-(2-Pyridyl)-5-(4-Pyridyl)-1,2,4-Triazole	MOFs	Others
2-(3-(Pyridin-4-yl)-1H-1,2,4-triazol-5-yl)pyridine (3-(2-Pyridyl)-5-(4-Pyridyl)-1,2,4-Triazole) is a metal-organic framework (MOF).

HY-W009401

*Boc-Ala(4-pyridyl)-OH*	Amino Acid Derivatives	Others
Boc-Ala(4-pyridyl)-OH is an alanine derivative .

HY-114799

*2-(4-Pyridyl)-4-methyl-thiazole-5-carboxylic acid* 4-Methyl-2-pyridin-4-ylthiazole-5-carboxylic acid	Drug Intermediate	Others
2-(4-Pyridyl)-4-methyl-thiazole-5-carboxylic acid (4-Methyl-2-pyridin-4-ylthiazole-5-carboxylic acid) is a synthetic intermediate useful for pharmaceutical synthesis.

HY-W009934

*2-Phenyl-2-(2-pyridyl)acetonitrile* α-Phenyl-2-pyridineacetonitrile	Drug Metabolite	Endocrinology
2-Phenyl-2-(2-pyridyl)acetonitrile is the major metabolite of SC 15396 metabolized by the supernatant fraction of rat liver homogenate. SC 15396 is an antigastrin that inhibits gastric secretion .

HY-W482593

4-(Di(1H-pyrrol-2-yl)methyl)pyridine 5-(4-Pyridyl)dipyrromethane	MOFs	Others
4-(Di(1H-pyrrol-2-yl)methyl)pyridine (5-(4-Pyridyl)dipyrromethane) is a metal-organic framework (MOF).

HY-W044805

*2-Amino-4-(4-pyridyl)-thiazole* 4-Pyridin-4-yl-thiazol-2-ylamine	Drug Intermediate	Others
2-Amino-4-(4-pyridyl)-thiazole (4-Pyridin-4-yl-thiazol-2-ylamine) is a synthetic intermediate useful for pharmaceutical synthesis.

HY-164794

Pyridyl disulfide-Dexamethasone	Glucocorticoid Receptor	Inflammation/Immunology
Pyridyl disulfide-Dexamethasone is a Dexamethasone (HY-14648) modified with pyridyl disulfide, which can be used for the synthesis of targeted peptide steroid conjugates .

HY-135367B

pyCTZ hydrochloride Pyridyl CTZ hydrochloride	Fluorescent Dye	Others
pyCTZ (Pyridyl CTZ) hydrochloride, a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ hydrochloride generates strong blue bioluminescence in the presence of luciferases. pyCTZ hydrochloride can be used for aequorin-based calcium sensing .

HY-135367

pyCTZ Pyridyl CTZ	Fluorescent Dye	Others
pyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ generates strong blue bioluminescence in the presence of luciferases. pyCTZ can be used for aequorin-based calcium sensing .

HY-135367A

pyCTZ TFA Pyridyl CTZ TFA	Fluorescent Dye	Others
pyCTZ (Pyridyl CTZ) TFA, a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ TFA generates strong blue bioluminescence in the presence of luciferases. pyCTZ TFA can be used for aequorin-based calcium sensing .

HY-114756

*2-(2-Pyridyl)-4-methyl-thiazole-5-carboxylic acid*	Drug Intermediate	Others
2-(2-Pyridyl)-4-methyl-thiazole-5-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.

HY-W127817

*Sn(IV) meso-tetra (4-pyridyl) porphine dichloride*	MOFs	Others
Sn(IV) meso-Tetra (4-Pyridyl) Porphine Dichloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W335656

*6-Methyl-2-pyridyl* 2-acetamido-2-deoxy-b-D-thioglucopyranoside**	Biochemical Assay Reagents	Others
6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside is used for glucose content determination.

HY-W768051

*rac 5-(3-Pyridyl)tetrahydro-2-furanone-d3*	Isotope-Labeled Compounds	Others
rac 5-(3-Pyridyl)tetrahydro-2-furanone-d₃ is the deuterium labeled rac 5-(3-Pyridyl)tetrahydro-2-furanone (HY-W777288).

HY-154575

*2-[(3-Pyridyl) pyrrolidin-1-yl]-2’-deoxyinosine*	Nucleoside Antimetabolite/Analog	Cancer
2-[(3-Pyridyl) pyrrolidin-1-yl]-2’-deoxyinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W009934R

*2-Phenyl-2-(2-pyridyl)acetonitrile (Standard)* α-Phenyl-2-pyridineacetonitrile (Standard)	Drug Metabolite Reference Standards	Endocrinology
2-Phenyl-2-(2-pyridyl)acetonitrile (Standard) is the analytical standard of 2-Phenyl-2-(2-pyridyl)acetonitrile. This product is intended for research and analytical applications. 2-Phenyl-2-(2-pyridyl)acetonitrile is the major metabolite of SC 15396 metabolized by the supernatant fraction of rat liver homogenate. SC 15396 is an antigastrin that inhibits gastric secretion[1].

HY-148180

Antimycobacterial agent-4	Bacterial Parasite	Infection
Antimycobacterial agent-4 is a 2-amino-4-(2-pyridyl) thiazole derivative, with antimycobacterial activity, antiplasmodial activity, and cytotoxicity on a mammalian cell line .

HY-W112286

*5,10,15,20-Tetra (4-pyridyl)-21H, 23H-porphyrin zinc* meso-Tetra (4-Pyridyl) porphine-Zn(II)	MOFs	Others
5,10,15,20-Tetra (4-pyridyl)-21H, 23H-porphyrin zinc (meso-Tetra (4-pyridyl) porphine-Zn(II)) is a metal-organic framework (MOF).

HY-139129

*N-(3-Pyridyl)indomethacinamide*	COX	Inflammation/Immunology
N-(3-Pyridyl)indomethacinamide is a derivative of Indomethacin (HY-14397). N-(3-Pyridyl)indomethacinamide is a COX2 inhibitor .

HY-W289542

*N-(2-Pyridyl)nicotinamide*	Bacterial	Infection
N-(2-Pyridyl)nicotinamide (Compound 3i) is an anti-biofilm agent. N-(2-Pyridyl)nicotinamide inhibits the formation of Bacillus subtilis biofilms .

HY-W019817S1

*4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d3*	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d₃ is the deuterium labeled 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (HY-W019817). 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is the main metabolite of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific lung carcinogen. The oxidative metabolic pathway in which NNAL is oxidized to NNK and other products exhibits carcinogenic activity. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol can be used in research on carcinogenic mechanisms related to lung cancer .

HY-W112935

*Ni(ii) meso-tetra(n-methyl-4-pyridyl) porphine tetrachloride* Nickel(II) meso -tetra(N-methyl-4-Pyridyl)porphine tetrachloride	MOFs	Others
Ni(ii) meso-?tetra(n-?methyl-?4-?pyridyl) porphine tetrachloride(Nickel(II) meso -tetra(N-methyl-4-pyridyl)porphine tetrachloride) is a metal-organic framework (MOF).

HY-W034938

*4'-(4-Pyridyl)-2,2':6',2''-terpyridine*	MOFs	Others
4'-(4-Pyridyl)-2,2':6',2''-terpyridine is a metal-organic framework (MOF).

HY-W112595

*2,7-Bis(4-pyridyl)-9,9-diethylfluorene*	MOFs	Others
2,7-Bis(4-pyridyl)-9,9-diethylfluorene is a metal-organic framework (MOF).

HY-W112287

*5,10,15,20-Tetra (4-pyridyl) porphyrin iron*	MOFs	Others
5,10,15,20-Tetra (4-pyridyl) porphyrin iron is a metal-organic framework (MOF).

HY-W038394

*1,3-Di(2-pyridyl)-1,3-propanedione* Dipicolinoylmethane	MOFs	Others
1,3-Di(2-pyridyl)-1,3-propanedione (Dipicolinoylmethane) is a metal-organic framework (MOF).

HY-W657003

*1,3-Bis[4-(4-Pyridyl)-2-thiazolyl]benzene*	MOFs	Others
1,3-Bis[4-(4-Pyridyl)-2-thiazolyl]benzene is a metal-organic framework (MOF).

HY-W329522

*Ethyl-2-(2-pyridyl)-4-(bromomethyl)-Thiazole-5-Carboxylate*	Drug Intermediate	Others
Ethyl-2-(2-pyridyl)-4-(bromomethyl)-Thiazole-5-Carboxylate is a synthetic intermediate useful for pharmaceutical synthesis.

HY-W674133

*2,4,6-Tris(3-Pyridyl)-1,3,5-triazine*	MOFs	Others
2,4,6-Tris(3-Pyridyl)-1,3,5-triazine is a metal-organic framework (MOF).

HY-W594564

*N,N′-Bis(4-pyridyl)urea*	MOFs	Others
N,N′-Bis(4-pyridyl)urea is a metal-organic framework (MOF).

HY-W038414

*3,5-Di(2-pyridyl)pyrazole*	MOFs	Others
3,5-Di(2-pyridyl)pyrazole is a metal-organic framework (MOF).

HY-W112606

*2,6-Bis(4-pyridyl)toluene*	MOFs	Others
2,6-Bis(4-pyridyl)toluene is a metal-organic framework (MOF).

Cat. No.	Product Name	Chemical Structure

HY-126477S

NNK-d4
NNK-d₄ is the deuterium labeled NNK .

HY-W768051

*rac 5-(3-Pyridyl)tetrahydro-2-furanone-d3*
rac 5-(3-Pyridyl)tetrahydro-2-furanone-d₃ is the deuterium labeled rac 5-(3-Pyridyl)tetrahydro-2-furanone (HY-W777288).

HY-Y0743S

1-(Pyridin-2-yl)ethan-1-one-d6
1-(Pyridin-2-yl)ethan-1-one-d₆ is deuterated labeled 1-(Pyridin-2-yl)ethan-1-one.

HY-W019817S1

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d3

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d₃ is the deuterium labeled 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (HY-W019817). 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is the main metabolite of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific lung carcinogen. The oxidative metabolic pathway in which NNAL is oxidized to NNK and other products exhibits carcinogenic activity. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol can be used in research on carcinogenic mechanisms related to lung cancer .

HY-W739426

4-Hydroxy-1-(pyridin-3-yl)butan-1-one-d4
4-Hydroxy-1-(pyridin-3-yl)butan-1-one-d₄ (4-Hydroxy-1-(3-pyridyl)-1-butanone-d₄) is the deuterium labeled 4-Hydroxy-1-(pyridin-3-yl)butan-1-one (HY-W270498).

Cat. No.	Product Name		Classification

HY-158705

SAINT-2		Cationic Lipids
SAINT-2 is a cationic lipid with gene transfection activity and is a pyridyl lipid analog. Molecular membranes prepared by SAINT-2 can interact with plasmids to form lipid complexes. After the complex is taken up by cells, the plasmid dissociates from the lipid complex under the action of DOPE and the plasmid translocates across the endosome and/or nuclear membrane. Thus, SAINT-2 effectively transfers small oligonucleotides into cells .

HY-154575

*2-[(3-Pyridyl) pyrrolidin-1-yl]-2’-deoxyinosine*		Nucleoside Analogs Inosine
2-[(3-Pyridyl) pyrrolidin-1-yl]-2’-deoxyinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

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