76014-81-8
Chemical Structure
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol
Synonym(s): NNAL
- CAS. Nr.: 76014-81-8
- Formula:C10H15N3O2
- Molecular Weight:209.25
IUPAC Name: N-(4-hydroxy-4-(pyridin-3-yl)butyl)-N-methylnitrous amide
InChIKey: OGRXKBUCZFFSTL-UHFFFAOYSA-N
SMILES: O=NN(CCCC(C1=CC=CN=C1)O)C
Biological Activity: 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is the main metabolite of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific lung carcinogen. The oxidative metabolic pathway in which NNAL is oxidized to NNK and other products exhibits carcinogenic activity. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol can be used in research on carcinogenic mechanisms related to lung cancer[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol | 99.94% | 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is the main metabolite of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific lung carcinogen. The oxidative metabolic pathway in which NNAL is oxidized to NNK and other products exhibits carcinogenic activity. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol can be used in research on carcinogenic mechanisms related to lung cancer. | ||||||||||||||||||||
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4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d3 | 98.49% | 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d3 is the deuterium labeled 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (HY-W019817). 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is the main metabolite of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific lung carcinogen. The oxidative metabolic pathway in which NNAL is oxidized to NNK and other products exhibits carcinogenic activity. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol can be used in research on carcinogenic mechanisms related to lung cancer. | ||||||||||||||||||||
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