7272-84-6
Chemical Structure
3-(4-Pyridyl)indole
Synonym(s): Rockout; 3-(4-Pyridinyl)-1H-indole; Rho Kinase Inhibitor III, Rockout
- CAS. Nr.: 7272-84-6
- Formula:C13H10N2
- Molecular Weight:194.23
IUPAC Name: 3-(pyridin-4-yl)-1H-indole
InChIKey: LLJRXVHJOJRCSM-UHFFFAOYSA-N
SMILES: C1(C2=CC=NC=C2)=CNC3=C1C=CC=C3
Biological Activity: 3-(4-Pyridyl)indole (Rockout; 3-(4-Pyridinyl)-1H-indole; Rho Kinase Inhibitor III, Rockout) is a Rho-kinase inhibitor (IC50 = 25 μM). 3-(4-Pyridyl)indole inhibits cell migration, membrane blebbing, and stress fiber and focal adhesion formation, and induces actin stress fiber disassembly. 3-(4-Pyridyl)indole promotes cell spreading and alters cell morphology and dynamics. 3-(4-Pyridyl)indole inhibits PRK2. 3-(4-Pyridyl)indole is used in wound healing research[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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3-(4-Pyridyl)indole | 99.94% | 3-(4-Pyridyl)indole (Rockout; 3-(4-Pyridinyl)-1H-indole; Rho Kinase Inhibitor III, Rockout) is a Rho-kinase inhibitor (IC50 = 25 μM). 3-(4-Pyridyl)indole inhibits cell migration, membrane blebbing, and stress fiber and focal adhesion formation, and induces actin stress fiber disassembly. 3-(4-Pyridyl)indole promotes cell spreading and alters cell morphology and dynamics. 3-(4-Pyridyl)indole inhibits PRK2. 3-(4-Pyridyl)indole is used in wound healing research. | ||||||||||||||||||||
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