2 Results for "

RNF5 agonist 1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "RNF5 agonist 1" in MCE Product Catalog:

Cat. No.: HY-170515
CAS No.: 69909-92-8
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Inflammation/Immunology

RNF5 agonist 1 (analog-1), a structural analog of RNF5 inhibitor inh-02 (HY-123967), is a potent RNF5 agonist. RNF5 agonist 1 increases the ubiquitylation status of ATG4B in F508del-CFTR-expressing CFBE41o- cells .
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Cat. No.: HY-170515A
CAS No.: 2231731-82-9
(E),(Z)-RNF5 agonist 1 (Compound Analog-1) is a RNF5 agonist that can enhance the ubiquitination and degradation of SARS-CoV-2 E protein by RNF5. (E),(Z)-RNF5 agonist 1 effectively inhibits the replication of SARS-CoV-2 and significantly alleviates pulmonary pathological damage and systemic inflammatory response in mouse infection models. (E),(Z)-RNF5 agonist 1 has a strong cytotoxic effect on neuroblastoma and melanoma. (E),(Z)-RNF5 agonist 1 can be used for research on anti-cancer and anti-viral purposes .
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