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Results for "

Rapamycin (Standard)

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Natural
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Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-10219R
    Rapamycin (Standard)

    Sirolimus (Standard); AY-22989 (Standard); NSC 226080 (Standard)

    		 Reference Standards mTOR FKBP Fungal Autophagy Endogenous Metabolite Antibiotic Bacterial Cancer
    Rapamycin (Standard) is the analytical standard of Rapamycin (HY-10219). This product is intended for research and analytical applications. Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1 . Rapamycin is an autophagy activator, an immunosuppressant .
    Rapamycin (Standard)
  • HY-10218R
    Everolimus (Standard)

    RAD001 (Standard); SDZ-RAD (Standard)

    		 Reference Standards mTOR FKBP Autophagy Apoptosis Bacterial Cancer
    Everolimus (Standard) is the analytical standard of Everolimus. This product is intended for research and analytical applications. Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities .
    Everolimus (Standard)
  • HY-19555AR
    Seco Rapamycin sodium salt (Standard)

    SecoRapamycin A monosodium (Standard)

    		 Reference Standards Drug Metabolite Others
    Phenglutarimid (hydrochloride) (Standard) is the analytical standard of Phenglutarimid (hydrochloride). This product is intended for research and analytical applications. Phenglutarimid hydrochloride is an anticholinergic used as an antiparkinsonian agent.
    Seco Rapamycin sodium salt (Standard)
  • HY-101920R
    Autophinib (Standard)

    		Reference Standards Autophagy PI3K Neurological Disease Cancer
    Autophinib (Standard) is the analytical standard of Autophinib (HY-101920). This product is intended for research and analytical applications. Autophinib is a potent, selective autophagy inhibitor with IC50s of 90 nM and 40 nM for starvation- and Rapamycin-induced autophagy, respectively. Autophinib is also an ATP competitive Vacuolar Protein Sorting 34 (VPS34) inhibitor with an IC50 of 19 nM. Autophinib inhibits autophagy induced by starvation or Rapamycin by targeting VPS34 .
    Autophinib (Standard)

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