Rapamycin (Standard)
Based on 1 publication(s) in Google Scholar
Rapamycin (Standard) (Sirolimus (Standard)) is the analytical standard of Rapamycin (HY-10219). This product is intended for research and analytical applications. Rapamycin (Sirolimus; AY 22989) is a potent and specific blood-brain barrier-transmissible mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin is a molecular glue that binds FKBP12 and mTOR proteins together, thereby inhibiting mTOR kinase activity. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.
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- Reinheit : 98.98%
- CAS. Nr.: 53123-88-9
- Formel: C51H79NO13
- Molecular Weight:914.17
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
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HY-10219
RapamycinmTOR Inhibitor -
HY-10218
EverolimusmTORC Inhibitor -
HY-13328
SapanisertibmTORC1/mTORC2 Inhibitor -
HY-13756A
Tacrolimus monohydrateCalcineurin Inhibitor -
HY-13756R
Tacrolimus (Standard)Reference Standard -
HY-13003
Torin 1mTOR Inhibitor -
HY-10219G
Rapamycin (GMP)mTOR Inhibitor -
HY-10219GL
Rapamycin (GMP Like)mTOR Inhibitor -
HY-10218R
Everolimus (Standard)mTORC Inhibitor -
HY-10422
AZD-8055mTOR Inhibitor -
HY-15247
VistusertibmTORC Inhibitor -
HY-13756
TacrolimusCalcineurin Inhibitor
Publications Citing Use of MedChemExpress (MCE) Rapamycin (Standard)
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Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 53123-88-9
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Appearance Solid
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Molecular Weight 914.17
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Formel C51H79NO13
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Color White to off-white
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SMILES
O=C([C@@]1(O)[C@@H](CC[C@@H](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@@H](C)C([C@@H]([C@@H](/C(C)=C/[C@H]2C)O)OC)=O)C)OC)O1)C)C(N3CCCC[C@H]3C(O[C@@H](CC2=O)[C@@H](C[C@H]4C[C@H]([C@H](O)CC4)OC)C)=O)=O
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Synonyms
Sirolimus (Standard); AY-22989 (Standard); NSC 226080 (Standard)
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
Reinheit & Dokumentation
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Rapamycin (Standard) Related Classifications
HY-10219R Related Classifications
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Keywords
- Rapamycin (Standard)
- 53123-88-9
- Sirolimus (Standard)
- AY-22989 (Standard)
- NSC 226080 (Standard)
- Reference Standards
- mTOR
- FKBP
- Molecular Glues
- Fungal
- Autophagy
- Endogenous Metabolite
- Antibiotic
- Bacterial
- Mammalian target of Rapamycin
- FK506-binding protein
- HEK293
- FKBP12
- mTORC1
- autophagy
- immunosuppressant
- Inhibitor
- inhibitor
- inhibit