1 Result for "

SCH-900875

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SCH-900875" in MCE Product Catalog:

Cat. No.: HY-165428
CAS No.: 907206-98-8
Target:  

CXCR Arrestin

Research Areas:  

Inflammation/Immunology

SCH-900875 is an orally active, brain-penetrant and selective CXCR3 receptor inhibitor, which also shows high selectivity over CXCR1 and CXCR2 receptors. SCH-900875 binds to CXCR3, blocking the binding of ligands CXCL9, CXCL10, and CXCL11, inhibiting downstream G protein and β-arrestin signaling pathways to suppress inflammatory cell migration. SCH-900875 is promising for research of autoimmune diseases (rheumatoid arthritis, multiple sclerosis) and inflammatory disorders (psoriasis, inflammatory bowel disease) .
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