1 Result for "

SGX-393

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SGX-393" in MCE Product Catalog:

Cat. No.: HY-165532
CAS No.: 1030610-86-6
Synonyms: SGX70393
Target:  

Bcr-Abl

Research Areas:  

Cancer

SGX393 (SGX70393) is a Bcr-Abl kinase inhibitor. SGX393 binds to the active conformation of the kinase domains of both wild-type and T315I mutant Bcr-Abl, thereby inhibiting kinase activity. SGX393 exhibits antiproliferative effects in cells expressing wild-type or T315I mutant Bcr-Abl, and suppresses T315I-driven tumor growth. SGX393 can be used for the research of chronic myeloid leukemia .
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