1 Result for "

SHP2-IN-8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SHP2-IN-8" in MCE Product Catalog:

Cat. No.: HY-144396
CAS No.: 1801692-60-3
Research Areas:  

Cancer

SHP2-IN-8 is a highly potent, selective, and cellularly active allosteric SHP2 inhibitor with IC50 value of 23 nM and Ki of 22 nM. SHP2-IN-8 is reversible and noncompetitive. SHP2-IN-8 causes a significant thermal shift with the ΔTm of 7.01 °C. SHP2-IN-8 induces the apoptosis and inhibits the phosphorylation of AKT in Hela cells .
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