1 Result for "

SIRT6-IN-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SIRT6-IN-4" in MCE Product Catalog:

Cat. No.: HY-170402
CAS No.: 3075160-74-3
Target:  

Sirtuin Apoptosis

Research Areas:  

Cancer

SIRT6-IN-4 (Compound 10d) is a selective inhibitor for SIRT6 with an IC50 of 5.68 μM. SIRT6-IN-4 inhibits the proliferation of MCF-7 with an IC50 of 8.30 μM. SIRT6-IN-4 arrests the cell cycle at G2/M phase, inhibits thecell migration and invasion of MCF-7, and induces apoptosis. SIRT6-IN-4 exhibits antitumor efficacy in mouse models .
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