1 Result for "

SKLB-Y13

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SKLB-Y13" in MCE Product Catalog:

Cat. No.: HY-176848
Target:  

YTHDF Apoptosis MMP Caspase

Research Areas:  

Cancer

SKLB-Y13 is a selective YTHDF1 inhibitor with an IC50 of 0.76 μM and a KD of 5.097 μM. SKLB-Y13 binds to the Tyr397 and Trp470 residues in the m 6A-binding pocket of YTHDF1, disrupting the interaction between YTHDF1 and m 6A-modified mRNA. SKLB-Y13 inhibits cancer cell proliferation and promotes apoptosis. SKLB-Y13 is applicable to breast cancer-related research .
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